Skip to content
Project Directory
  • Français
Donate Now
  • Français
  • About
    • What We Do
    • EDI Action Plan
    • Leadership
    • Team
    • Annual Report
    • Publications
    • Careers
  • Brain Conditions
    • One Brain
    • ALS
    • Autism (ASD)
    • Brain Cancer
    • Brain Injury
    • Dementia
    • Epilepsy
    • Mental Illness
    • Multiple Sclerosis
    • Parkinson’s
    • Stroke
    • More
  • Research
    • Programs
    • Funding Opportunities
    • Program Partners
    • Announcements
  • Impact
    • Research Impact Stories
    • Equity, Diversity and Inclusion
    • Brain Health in Indigenous Communities
    • Women’s Brain Health
    • Mind Over Matter
  • How You Can Help
    • Ways to Give
    • Start a Fundraiser
    • Workplace Giving
    • The Great Minds

Funded Grants

Back to results

Novel First-In-Class Melatonin MT2 Receptor Agonist for Neuropathic Pain: Investigational New Drug (IND) – Enabling Studies

Project Overview

Neuropathic pain is a chronic pain disorder resulting from damage to the nerves.  It may be due to cancer, diabetes or conditions like fibromyalgia. Neuropathic pain is often eased by antidepressant or anti-epileptic medicines but most often treated with opioids. Opioid use is associated with serious adverse effects such as addiction and death by overdose. Research on novel analgesic drugs for the treatment of neuropathic pain is thus apriority. Gabriella Gobbi and her team at their laboratory at McGill University have previously designed, synthesized and validated a novel analgesic drug in animal models that may be beneficial in treating neuropathic pain in humans without the side effects that usually occur with opioids. In this project, they will be able to conduct essential pharmacological and toxicological studies and submit an Investigational New Drug (IND) application to obtain the required permission from the regulatory authorities to begin human clinical testing.

Principal Investigator

Gabriella Gobbi , McGill University

Team Members

Mark Ware, McGill University

Robert Zamboni, McGill University

Stefano Comai, McGill University

Partners and Donors

CQDM

McGill University

Delmar Chemicals Inc.

Project Complete

Novel First-In-Class Melatonin MT2 Receptor Agonist for Neuropathic Pain: Investigational New Drug (IND) – Enabling Studies

  • Grant Type

    Team grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    CQDM - Brain Canada - SynergiQc

  • Province

    Québec

  • Start Date

    2019

  • Total Grant Amount

    $1,600,000

  • Health Canada Contribution

    $453,125

Contact Us

1200 McGill College Avenue
Suite 1600, Montreal, Quebec
H3B 4G7

+1 (514) 989-2989 info@braincanada.ca

Please note all online donations will receive an electronic tax receipt, issued by Brain Canada Foundation.

Our Donors

Playing with Marbles Podcast

Join us and take a journey to the real last great frontier – the brain.

Listen

Subscribe to Brain News

Receive our monthly electronic newsletter with updates on funded projects, upcoming events and breakthroughs in brain research.

Sign Up

Territorial acknowledgement

The offices of Brain Canada Foundation are located on the traditional, ancestral territory of the Kanien'kehá:ka Peoples, a place which has long served as a site of meeting and exchange amongst nations. We honour and pay respect to elders past, present and emerging, and dedicate ourselves to moving forward in the spirit of partnership, collaboration, and reconciliation. In our work, we focus our efforts on the Truth and Reconciliation Commission’s Calls to Action, particularly those that pertain to improving health for Indigenous Peoples and that focus on advancing our own learning on Indigenous issues.

© 2025 Brain Canada Foundation

Registration number: 89105 2094 RR0001

  • Terms and Conditions
  • Privacy Policy

Design by Field Trip & Co