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ShARP: Screenable assays for RNA-binding proteins involved in brain disorders and diseases
https://braincanada.ca/funded-grants/sharp-screenable-assays-for-rna-binding-proteins-involved-in-brain-disorders-and-diseasesBrain disorders such as autism, major depressive disorder and Alzheimer’s disease are among the greatest medical challenges of our era. Project Overview Brain disorders such as autism, major depressive disorder and Alzheimer’s disease are among the greatest medical challenges of our era. Many drugs...
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Shifting paradigms, informing solutions
https://braincanada.ca/about/news-updates/shifting-paradigms-informing-solutionsIn 2016, Yasser Iturria-Medina, Ph.D., and his post-doctoral supervisor at the time, Alan Evans, Ph.D., published findings that quietly helped shift how scientists think about Alzheimer’s disease. Today, that work has informed several therapeutic patents and opened the door to a distinct class...
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Shifting perspectives in Parkinson’s disease: can peripheral immune cells induce neurodegeneration without vascular transmigration
https://braincanada.ca/funded-grants/shifting-perspectives-in-parkinson-s-disease-can-peripheral-immune-cells-induce-neurodegeneration-without-vascular-transmigrationShifting perspectives in Parkinson's disease: can peripheral immune cells induce neurodegeneration without vascular transmigration? Parkinson’s disease (PD) is the second most common neurodegenerative disorder in the world and affects over 100,000 Canadians. It causes movement difficulties and...
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Shortening the timeline for ALS treatments
https://braincanada.ca/about/news-updates/shortening-the-timeline-for-als-treatmentsDr. Carlos Rodrigo Camara-Lemarroy is an early-career researcher and clinical neurologist based in Canada at the University of Calgary. He is a first-time recipient of an ALS Canada-Brain Canada research grant. Can this routine and inexpensive procedure have a neuroprotective effect in ALS? Award:...
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SHRF and Brain Canada announce partnership to invest in Saskatchewan Brain Health Solutions
https://braincanada.ca/about/news-updates/shrf-and-brain-canada-announce-partnership-to-invest-in-saskatchewan-brain-health-solutionsSaskatchewan Health Research Foundation (SHRF) and Brain Canada make a two-year commitment to fund Saskatchewan Brain Health research through SHRF’s Solutions Program. Brain Health is essential for physical health and a fundamental pre-requisite for mental health and well-being throughout our lives....
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Signatures of early life stress as a risk factor for Alzheimer’s disease
https://braincanada.ca/funded-grants/signatures-of-early-life-stress-as-a-risk-factor-for-alzheimer-s-diseaseOur project investigates how childhood stress may increase the risk of developing Alzheimer’s Disease (AD) later in life. Project Overview Our project investigates how childhood stress may increase the risk of developing Alzheimer’s Disease (AD) later in life. We know that stress during early...
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Significance of native PEG-PLGA nanoparticles in the treatment of Alzheimer’s disease pathology
https://braincanada.ca/funded-grants/significance-of-native-peg-plga-nanoparticles-in-the-treatment-of-alzheimer-s-disease-pathologyAt present, there is no effective treatment to arrest the progression of Alzheimer disease (AD) - the most common cause of dementia affecting the elderly. The disease is caused by accumulation of two distinct clumps of proteins in the brain called neuritic plaques and neurofibrillary tangles formed...
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Significant funding boost for research on Alzheimer’s and ALS
https://braincanada.ca/about/news-updates/significant-funding-boost-for-research-on-alzheimer-s-and-alsDr. Meaghan O'Reilly, Sunnybrook Research Institute and the University of Toronto (left), and Dr. Liang Li, University of Alberta. Scientists from University of Toronto and University of Alberta, and their multinational teams, receive funding support from Brain Canada and CIHR Brain Canada and the...
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Single-cell multi-omics to uncover mechanisms of patient glioblastoma heterogeneity and recurrence
https://braincanada.ca/funded-grants/single-cell-multi-omics-to-uncover-mechanisms-of-patient-glioblastoma-heterogeneity-and-recurrenceBrain cancer is rarely curative and urgently needs novel transformative treatments. Project Overview Brain cancer is rarely curative and urgently needs novel transformative treatments. Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. It is also among the most...
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Six early-career researchers receive leadership grants
https://braincanada.ca/about/news-updates/six-early-career-researchers-receive-leadership-grantsBrain Canada program supports paradigm-shifting neuroscience that improves the lives of Canadians Read the full article here.