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A physiologic-to-tissue level approach to characterize the pathophysiology of hypoxic ischemic brain injury in humans.
https://braincanada.ca/funded-grants/a-physiologic-to-tissue-level-approach-to-characterize-the-pathophysiology-of-hypoxic-ischemic-brain-injury-in-humansDuring a cardiac arrest, when the heart stops beating, blood flow and the delivery of the oxygen to the brain stops. Project Overview During a cardiac arrest, when the heart stops beating, blood flow and the delivery of the oxygen to the brain stops. This lack of blood flow and oxygen leads to a...
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A pilot randomized-controlled trial evaluating the efficacy of a Live-Online Mindfulness-Based Intervention for Children with Juvenile Idiopathic Arthritis and their Families’: The Making Mindfulness Matter© in Children with Juvenile Idiopathic Arthritis Study.
https://braincanada.ca/funded-grants/a-pilot-randomized-controlled-trial-evaluating-the-efficacy-of-a-live-online-mindfulness-based-intervention-for-children-with-juvenile-idiopathic-arthritis-and-their-families-the-making-mindfulness-matter-in-children-with-juvenile-idiopathic-arthritis-studyThe goal of our research study is to better understand the comorbidity of mental health and disease in a sample of children with juvenile idiopathic arthritis (JIA) and their primary caregiver(s). Project Overview The goal of our research study is to better understand the comorbidity of mental...
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A Pilot Randomized Trial of a Digital App, WhatMatters to enable Person-Centred Care
https://braincanada.ca/funded-grants/a-pilot-randomized-trial-of-a-digital-app-whatmatters-to-enable-person-centred-carePerson-centred care is vital for dementia patients in hospitals to prevent stress-induced behaviors. Project Overview Person-centred care is vital for dementia patients in hospitals to prevent stress-induced behaviors. My team has developed WhatMatters, an app that allows family members to remotely...
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A platform for partnership
https://braincanada.ca/about/news-updates/a-platform-for-partnershipWritten Submission for the Pre-Budget Consultations in Advance of the Upcoming Federal Budget 2025 to improve brain health: Amplifying and accelerating brain research, for the benefit of all Canadians This brief presents our case for ongoing, sustained investment into the platform for partnership...
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A powerful collaboration offers crucial insights at the frontier of ALS biology
https://braincanada.ca/about/news-updates/a-powerful-collaboration-offers-crucial-insights-at-the-frontier-of-als-biologyDr. Hyun Kate Lee (left) and Dr. Ji_Young Youn “We think these questions are important for understanding the biology of ALS-causing genes and how they contribute to disease. We do our work out of curiosity, but also because we want to help and empower patients.” – Dr. Hyun Kate Lee Our...
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A powerful new partnership is bringing together two innovative national organizations working to advance brain health
https://braincanada.ca/about/news-updates/a-powerful-new-partnership-is-bringing-together-two-innovative-national-organizations-working-to-advance-brain-healthThe Kids Brain Health Network (KBHN) and Brain Canada Foundation are announcing a new collaboration to identify, support, and fund new research projects that strive to make a difference in the lives of children with neurodevelopmental disabilities and their families across Canada. "KBHN has a...
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A prodepressive dopamine receptor complex in brain mediates sex differences in depression and anxiety: validation and strategies for drug discovery
https://braincanada.ca/funded-grants/a-prodepressive-dopamine-receptor-complex-in-brain-mediates-sex-differences-in-depression-and-anxiety-validation-and-strategies-for-drug-discoveryMajor depression is common, highly prevalent, potentially lethal, affecting 10% of individuals with significant increase between 2015-2020, and 2-3-fold higher incidence in women compared to men. Project Overview Major depression is common, highly prevalent, potentially lethal, affecting 10% of...
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A Quartet, a Plan, a Team: Building a Patient Database to understand Progression in Multiple Sclerosis
https://braincanada.ca/about/news-updates/a-quartet-a-plan-a-team-building-a-patient-database-to-understand-progression-in-multiple-sclerosisLarry Lynd, Ph.D., University of British Columbia; Anthony Traboulsee, M.D., University of British Columbia; Alexandre Prat, M.D., Ph.D., Centre de Recherche du CHUM; Scott Patten, M.D., Ph.D., University of Calgary; Jiwon Oh, M.D., Ph.D., University of Toronto; Roger Tam, Ph.D., University of...
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A Randomized Controlled Trial of Pimozide in Subjects with ALS
https://braincanada.ca/funded-grants/a-randomized-controlled-trial-of-pimozide-in-subjects-with-alsThis project is a Phase II study involving 100 participants across 8 ALS clinics across Canada. The trial, led by the Principal Investigator of the Canadian Neuromuscular Disease Registry (CNDR) and the Chair of the Canadian ALS Research Network (CALS) will examine whether pimozide, a drug already...
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A Randomized Sham-Controlled Trial of Accelerated Intermittent Theta Burst Stimulation for Treatment Resistant Depression
https://braincanada.ca/funded-grants/a-randomized-sham-controlled-trial-of-accelerated-intermittent-theta-burst-stimulation-for-treatment-resistant-depressionBy 2050, over 1 million Canadians will suffer from depression; many of whom will not respond to traditional antidepressant medication, known to as treatment resistant depression (TRD). Project Overview By 2050, over 1 million Canadians will suffer from depression; many of whom will not respond to...
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