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A powerful collaboration offers crucial insights at the frontier of ALS biology
https://braincanada.ca/about/news-updates/a-powerful-collaboration-offers-crucial-insights-at-the-frontier-of-als-biologyDr. Hyun Kate Lee (left) and Dr. Ji_Young Youn “We think these questions are important for understanding the biology of ALS-causing genes and how they contribute to disease. We do our work out of curiosity, but also because we want to help and empower patients.” – Dr. Hyun Kate Lee Our...
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A powerful new partnership is bringing together two innovative national organizations working to advance brain health
https://braincanada.ca/about/news-updates/a-powerful-new-partnership-is-bringing-together-two-innovative-national-organizations-working-to-advance-brain-healthThe Kids Brain Health Network (KBHN) and Brain Canada Foundation are announcing a new collaboration to identify, support, and fund new research projects that strive to make a difference in the lives of children with neurodevelopmental disabilities and their families across Canada. "KBHN has a...
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A prodepressive dopamine receptor complex in brain mediates sex differences in depression and anxiety: validation and strategies for drug discovery
https://braincanada.ca/funded-grants/a-prodepressive-dopamine-receptor-complex-in-brain-mediates-sex-differences-in-depression-and-anxiety-validation-and-strategies-for-drug-discoveryMajor depression is common, highly prevalent, potentially lethal, affecting 10% of individuals with significant increase between 2015-2020, and 2-3-fold higher incidence in women compared to men. Project Overview Major depression is common, highly prevalent, potentially lethal, affecting 10% of...
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A Quartet, a Plan, a Team: Building a Patient Database to understand Progression in Multiple Sclerosis
https://braincanada.ca/about/news-updates/a-quartet-a-plan-a-team-building-a-patient-database-to-understand-progression-in-multiple-sclerosisLarry Lynd, Ph.D., University of British Columbia; Anthony Traboulsee, M.D., University of British Columbia; Alexandre Prat, M.D., Ph.D., Centre de Recherche du CHUM; Scott Patten, M.D., Ph.D., University of Calgary; Jiwon Oh, M.D., Ph.D., University of Toronto; Roger Tam, Ph.D., University of...
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A Randomized Controlled Trial of Pimozide in Subjects with ALS
https://braincanada.ca/funded-grants/a-randomized-controlled-trial-of-pimozide-in-subjects-with-alsThis project is a Phase II study involving 100 participants across 8 ALS clinics across Canada. The trial, led by the Principal Investigator of the Canadian Neuromuscular Disease Registry (CNDR) and the Chair of the Canadian ALS Research Network (CALS) will examine whether pimozide, a drug already...
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A Randomized Sham-Controlled Trial of Accelerated Intermittent Theta Burst Stimulation for Treatment Resistant Depression
https://braincanada.ca/funded-grants/a-randomized-sham-controlled-trial-of-accelerated-intermittent-theta-burst-stimulation-for-treatment-resistant-depressionBy 2050, over 1 million Canadians will suffer from depression; many of whom will not respond to traditional antidepressant medication, known to as treatment resistant depression (TRD). Project Overview By 2050, over 1 million Canadians will suffer from depression; many of whom will not respond to...
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A research platform to study animal and human cellular models of neurological disorders
https://braincanada.ca/funded-grants/a-research-platform-to-study-animal-and-human-cellular-models-of-neurological-disordersNeurological diseases including neurodegenerative, neurodevelopmental, and psychiatric disorders are collectively one of the leading causes of disability to the Canadian population. Project Overview Neurological diseases including neurodegenerative, neurodevelopmental, and psychiatric disorders are...
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A Ride to Remember 2020
https://braincanada.ca/about/news-updates/a-ride-to-remember-2020Montreal family takes life by the handlebars, and raises funds for brain research. Helping to bathe and dress your grandfather is not a typical responsibility for a 17-year-old Montreal high school student. But even as teenagers, Matthew and Evan Wener were all too aware of the toll caring for a...
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A Ride to Remember 2020
https://braincanada.ca/about/news-updates/a-ride-to-remember-2020-2Montreal family takes life by the handlebars, and raises funds for brain research Helping to bathe and dress your grandfather is not a typical responsibility for a 17-year-old Montreal high school student. But even as teenagers, Matthew and Evan Wener were all too aware of the toll caring for a...
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A sister’s love: Pushing ALS research forward
https://braincanada.ca/about/news-updates/a-sister-s-love-pushing-als-research-forwardLinda’s brother, Pierre, received an ALS diagnosis in 2017 at the age of 52 In 2017, Linda Auger Morissette’s brother, Pierre, received an amyotrophic lateral sclerosis (ALS) diagnosis at the age of 52. “This completely shocked my family,” she says. “My daughter, who views her uncle like a father,...