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A Soccer Player Turned Brain Health Adovcate
https://braincanada.ca/about/news-updates/a-soccer-player-turned-brain-health-adovcateJay Randhawa suffered a head injury during a soccer game that ended his career. “When you face adversity and opposition, you have two choices,” he says. “Stay down and give up or get up and fight!” Jay Randhawa was – quite literally – at the top of his game before a brain injury changed everything....
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A sustainable ecosystem of care for women with traumatic brain injury following intimate partner violence: First steps.
https://braincanada.ca/funded-grants/a-sustainable-ecosystem-of-care-for-women-with-traumatic-brain-injury-following-intimate-partner-violence-first-stepsWomen victims of intimate partner violence (IPV) are at high risk of traumatic brain injury (TBI). As many as 75% are thought to have sustained a TBI, though most remain undiagnosed and untreated, but nonetheless live with its lasting effects. Project Overview Women victims of intimate partner...
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A Teen’s Perspective: An interview with Sydney Marconi
https://braincanada.ca/about/news-updates/a-teen-s-perspective-an-interview-with-sydney-marconiSydney Marconi is a young Métis woman from Ottawa with ancestral ties to Kapawe’no First Nation, Treaty 8. At 15, Sydney survived a car accident that left her with catastrophic brain trauma. We asked her about her experience as a young person navigating the system after a TBI. You can read her...
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A “tipping point” neuron type driving Alzheimer’s Disease progression
https://braincanada.ca/funded-grants/a-tipping-point-neuron-type-driving-alzheimer-s-disease-progressionAlzheimer’s Disease (AD) is characterized by dysregulation of neurons involved in memory, which is believed to be caused by the production of an agent termed “amyloid beta”. Project Overview Alzheimer’s Disease (AD) is characterized by dysregulation of neurons involved in memory, which is believed...
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A unifying approach to treat multisystem proteinopathy and ALS using noninvasive novel ASO delivery
https://braincanada.ca/funded-grants/a-unifying-approach-to-treat-multisystem-proteinopathy-and-als-using-noninvasive-novel-aso-deliveryMultisystem proteinopathy (MSP) is a devastating rare disease described by a cluster of diseases that affect the brain, bone, and muscle. Project Overview Multisystem proteinopathy (MSP) is a devastating rare disease described by a cluster of diseases that affect the brain, bone, and muscle....
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A unique approach to regaining movement
https://braincanada.ca/about/news-updates/a-unique-approach-to-regaining-movementAccording to data collected by Public Health Agency of Canada, approximately 878,500 Canadian adults over the age of 20 have experienced a stroke, a sudden loss of brain function caused by a brain blood vessel blockage or rupture. Dr. Marco Bonizzato is exploring Brain-Computer Interfaces (BCIs) to...
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A universal platform for high volume genetic modifier testing in Tauopathy
https://braincanada.ca/funded-grants/a-universal-platform-for-high-volume-genetic-modifier-testing-in-tauopathyGenetic testing shows that the Tau gene can often carry changes (DNA mutations) in people with dementia, and also in people who are not yet diagnosed with dementia. Project Overview Genetic testing shows that the Tau gene can often carry changes (DNA mutations) in people with dementia, and also in...
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Aberrant tRNA function exacerbates TDP-43 misfolding and toxicity in cellular models of ALS
https://braincanada.ca/funded-grants/aberrant-trna-function-exacerbates-tdp-43-misfolding-and-toxicity-in-cellular-models-of-alsAberrant tRNA processing and function has the capacity to exacerbate misfolding of ALS-associated proteins and the ensuing toxicity. Project Overview Aberrant tRNA processing and function has the capacity to exacerbate misfolding of ALS-associated proteins and the ensuing toxicity. tRNAs mainly...
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Accelerating AI and Brain Research
https://braincanada.ca/about/news-updates/accelerating-ai-and-brain-researchAfter meeting with Parliamentarians in Ottawa, Brain Canada published a pan-Canadian consultation report highlighting a series of immediate AI and neuroscience research investment opportunities. The report reflects feedback received from eight AI brain research roundtables hosted by Brain...
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Accelerating Alzheimer’s Research
https://braincanada.ca/about/news-updates/accelerating-alzheimer-s-researchDr. Sylvia Villeneuve is accelerating research on Alzheimer’s across the globe. By sharing comprehensive data from preclinical Alzheimer’s disease (AD) patients, the Canadian Alzheimer’s Prevention Data Repository and Sharing (CAP) platform, headed by Villeneuve, is bolstering research studies...