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A novel immunotherapy based on genetically modified hematopoietic stem cells as a new hope for treating glioblastoma, an aggressive cancerous tumor of the brain
https://braincanada.ca/funded-grants/a-novel-immunotherapy-based-on-genetically-modified-hematopoietic-stem-cells-as-a-new-hope-for-treating-glioblastoma-an-aggressive-cancerous-tumor-of-the-brainLed by Dr. Elie Haddad from CHU Sainte-Justine in collaboration with Immugenia, this project includes an inter-provincial research collaboration Project Overview Led by Dr. Elie Haddad from CHU Sainte-Justine in collaboration with Immugenia, this project includes an inter-provincial research...
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A Novel Microfluidic Platform for Investigating Axonal Sprouting in Motor Neurons
https://braincanada.ca/funded-grants/a-novel-microfluidic-platform-for-investigating-axonal-sprouting-in-motor-neuronsMotor neurons are extremely complex cells. Not only do they have an intricate set of inner workings, but they have a long wire-like portion called an axon that connects the central nervous system to muscles called an axon. Project Overview Motor neurons are extremely complex cells. Not only do they...
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A Novel Zebrafish-Based Platform for Anticonvulsant Drug Development
https://braincanada.ca/funded-grants/a-novel-zebrafish-based-platform-for-anticonvulsant-drug-developmentEpilepsy is a common neurological condition that affects 1-2% of the population. Project Overview Epilepsy is a common neurological condition that affects 1-2% of the population. Despite dozens of anticonvulsant medications, over a third of patients remain refractory to drugs and our goal is to...
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A Patient-Derived hiPSC Neuronal Platform for Drug Discovery in Parkinson’s Disease and Amyotrophic Lateral Sclerosis
https://braincanada.ca/funded-grants/a-patient-derived-hipsc-neuronal-platform-for-drug-discovery-in-parkinson-s-disease-and-amyotrophic-lateral-sclerosisParkinson’s Disease (PD) and Amyotrophic Lateral Sclerosis (ALS) are two of the most common and devastating neurodegenerative diseases, affecting more than 2% of the population over the age of 65. Project Overview Parkinson’s Disease (PD) and Amyotrophic Lateral Sclerosis (ALS) are two of the most...
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A patient-derived iPSC platform of disease relevant cell models for biological studies
https://braincanada.ca/funded-grants/a-patient-derived-ipsc-platform-of-disease-relevant-cell-models-for-biological-studiesOne of the greatest advancements in science over the past 10 years is the development of induced pluripotent stem cells (iPSCs). Project Overview One of the greatest advancements in science over the past 10 years is the development of induced pluripotent stem cells (iPSCs). These cells make it...
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A personalized medicine approach to better understand the biology of bipolar disorder
https://braincanada.ca/about/news-updates/a-personalized-medicine-approach-to-better-understand-the-biology-of-bipolar-disorder -
A physiologic-to-tissue level approach to characterize the pathophysiology of hypoxic ischemic brain injury in humans.
https://braincanada.ca/funded-grants/a-physiologic-to-tissue-level-approach-to-characterize-the-pathophysiology-of-hypoxic-ischemic-brain-injury-in-humansDuring a cardiac arrest, when the heart stops beating, blood flow and the delivery of the oxygen to the brain stops. Project Overview During a cardiac arrest, when the heart stops beating, blood flow and the delivery of the oxygen to the brain stops. This lack of blood flow and oxygen leads to a...
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A pilot randomized-controlled trial evaluating the efficacy of a Live-Online Mindfulness-Based Intervention for Children with Juvenile Idiopathic Arthritis and their Families’: The Making Mindfulness Matter© in Children with Juvenile Idiopathic Arthritis Study.
https://braincanada.ca/funded-grants/a-pilot-randomized-controlled-trial-evaluating-the-efficacy-of-a-live-online-mindfulness-based-intervention-for-children-with-juvenile-idiopathic-arthritis-and-their-families-the-making-mindfulness-matter-in-children-with-juvenile-idiopathic-arthritis-studyThe goal of our research study is to better understand the comorbidity of mental health and disease in a sample of children with juvenile idiopathic arthritis (JIA) and their primary caregiver(s). Project Overview The goal of our research study is to better understand the comorbidity of mental...
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A Pilot Randomized Trial of a Digital App, WhatMatters to enable Person-Centred Care
https://braincanada.ca/funded-grants/a-pilot-randomized-trial-of-a-digital-app-whatmatters-to-enable-person-centred-carePerson-centred care is vital for dementia patients in hospitals to prevent stress-induced behaviors. Project Overview Person-centred care is vital for dementia patients in hospitals to prevent stress-induced behaviors. My team has developed WhatMatters, an app that allows family members to remotely...
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A platform for partnership
https://braincanada.ca/about/news-updates/a-platform-for-partnershipWritten Submission for the Pre-Budget Consultations in Advance of the Upcoming Federal Budget 2025 to improve brain health: Amplifying and accelerating brain research, for the benefit of all Canadians This brief presents our case for ongoing, sustained investment into the platform for partnership...
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