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More than 80 percent of people with Alzheimer’s disease experience agitation or show aggression. These common symptoms are the main reasons why people with Alzheimer’s disease end up in emergency rooms, are hospitalized and have to move from their homes to long-term care facilities. Read the full...

Late life is full of transitions, such as retirement and physical changes. For some people, these changes can cause stress that can lead to developing late-life depression. Finding effective ways to treat depression among older people is critical because depression may pose added risks at this stage...

TDP-43, SOD1, and FUS proteinopathies in vivo: interrogating prion-like mechanisms and drug rescue in zebrafish and ALS hiPSC-derived neuron xenotransplant models Project Overview TDP-43, SOD1, and FUS proteinopathies in vivo: interrogating prion-like mechanisms and drug rescue in zebrafish and ALS...

Feasibility RCT of a digital tool for management of bulbar disease in ALS. Project Overview Feasibility RCT of a digital tool for management of bulbar disease in ALS Losing the ability to speak and swallow/eat are among the most devastating consequences of amyotrophic lateral sclerosis (ALS)....

Stem cell researcher Dr. Freda Miller and colleagues have made some very exciting progress, taking a novel concept from the laboratory to preclinical trials and, finally, to human trials. Photo credit: Nathan Chan In medicine, it’s a long path from scientific concept to promising treatment. As a...

Adolescent participating in intervention research focused on classical conditioning – a key element underlying the placebo effect – of thermal perception in youth. Differences in thermal ratings in response to conditioned cues are being assessed, and this indicates either attenuated or amplified...

Study of perisynaptic Schwann cells contribution on NMJ reinnervation efficiency in ALS Project Overview Study of perisynaptic Schwann cells contribution on NMJ reinnervation efficiency in ALS Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by motoneurons loss and...

Dr. Gary Armstrong (left) and Dr. Eric Shoubridge Investigating the role of mutations in CHCHD10 using ALS cell and zebrafish genetic models “The more we understand about all these different genes that we’re discovering in the clinic, we can ask new and better questions in our labs. Major...

Canada has launched its first brain tumour registry in its battle to better treat the disease and avoid reliance on foreign data. Read the full article here.

Brain Canada is pleased to share that in partnership with the Azrieli Foundation and its Canadian Centre for Caregiving Excellence and led by The Canadian Institutes of Health Research (CIHR) the Knowledge Mobilization (KM) Hub Funding Opportunity, has been awarded to the Brain Health Resources And...