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Diabetes Canada and Brain Canada Team Up to Tackle Mental Health Challenges in Diabetes
https://braincanada.ca/about/news-updates/diabetes-canada-and-brain-canada-team-up-to-tackle-mental-health-challenges-in-diabetesDiabetes Canada and Brain Canada are pleased to announce a new partnership to support research into the intersection of diabetes and mental health. Together, Diabetes Canada and Brain Canada will award and co-fund two grants of $450,000 each over three years through the 2025 End Diabetes Awards. ...
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Diagnosing autism in the youngest of patients
https://braincanada.ca/about/news-updates/diagnosing-autism-in-the-youngest-of-patientsMore than 1 in 100 individuals are diagnosed with Autism Spectrum Disorder (ASD), with profound impacts on the quality of life of those who are affected and their families. Many parents of children with ASD identify concerns as early at 12-18 months of age, yet the average age of diagnosis remains...
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DIgital markers of Social Cognition for diagnosis & pRognosis in Neurodegeneration (DISCeRN)
https://braincanada.ca/funded-grants/digital-markers-of-social-cognition-for-diagnosis-prognosis-in-neurodegeneration-discern-2Impairments in social cognition (SC), such as difficulties in understanding emotions, social cues, and maintaining meaningful interactions, are key contributors to the loss of social inclusion and quality of life in individuals with neurodegenerative diseases (ND). Project Overview Impairments in...
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DIgital markers of Social Cognition for diagnosis & pRognosis in Neurodegeneration (DISCeRN)
https://braincanada.ca/funded-grants/digital-markers-of-social-cognition-for-diagnosis-prognosis-in-neurodegeneration-discernImpairments in social cognition (SC), such as difficulties in understanding emotions, social cues, and maintaining meaningful interactions, are key contributors to the loss of social inclusion and quality of life in individuals with neurodegenerative diseases (ND). Project Overview Impairments in...
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Direct microglial reprogramming to study Parkinson’s Disease
https://braincanada.ca/funded-grants/direct-microglial-reprogramming-to-study-parkinson-s-diseaseThe human brain is a complex organ that presents many challenges for neuroscientists. Project Overview The human brain is a complex organ that presents many challenges for neuroscientists. For instance, tissue availability represents a major problem given that this organ does not regenerates,...
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Discovering “hidden” causal mutations in autism using long-read RNAseq and proteomics in neuron development
https://braincanada.ca/funded-grants/discovering-hidden-causal-mutations-in-autism-using-long-read-rnaseq-and-proteomics-in-neuron-developmentAutism spectrum disorder (ASD) is a complex condition affecting communication, social interactions, and behavior in approximately 1–2% of people worldwide. Project Overview Autism spectrum disorder (ASD) is a complex condition affecting communication, social interactions, and behavior in...
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Discovering how brain cancer evolution affects responses to treatment
https://braincanada.ca/funded-grants/discovering-how-brain-cancer-evolution-affects-responses-to-treatmentA type of brain cancers called “diffuse gliomas” currently lacks effective treatments. Project Overview A type of brain cancers called “diffuse gliomas” currently lacks effective treatments. One obstacle to developing new therapies is the disease variability between patients. Several categories of...
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Discovery Grant gives lab capacity to deepen its focus on ALS
https://braincanada.ca/about/news-updates/discovery-grant-gives-lab-capacity-to-deepen-its-focus-on-als“This grant was so validating. It showed us that our questions, no matter how ‘out there’, were heading in the right direction.” – Dr. Maxime Rousseaux TDP-43 is a protein that lives in the nucleus of our cells. But in at least 97 per cent of ALS patients, TDP-43 somehow finds its way out of the...
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Discovery of Therapeutic Targets for FUS- and TDP43-Dependent Forms of ALS
https://braincanada.ca/funded-grants/discovery-of-therapeutic-targets-for-fus-and-tdp43-dependent-forms-of-alsThe four most commonly studied ALS proteins are SOD1, TDP-43, FUS and C9ORF72 Project Overview The four most commonly studied ALS proteins are SOD1, TDP-43, FUS and C9ORF72. Of these, TDP-43 and FUS have the most in common. Not only do they share similar functions inside cells, but in motor neurons...
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Discovery of transcriptomic biomarkers and epigenetic therapeutic targets for c9ALS and sALS
https://braincanada.ca/funded-grants/discovery-of-transcriptomic-biomarkers-and-epigenetic-therapeutic-targets-for-c9als-and-salsDr. Belzil began her research career as a PhD student at the Université de Montréal under the guidance of world renowned geneticist and Director of the Montreal Neurological Institute and Hospital, Dr. Guy Rouleau. Project Overview Dr. Belzil began her research career as a PhD student at the...