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The brain is estimated to contain 100 billion cells that form 100 trillion connections. Project Overview The brain is estimated to contain 100 billion cells that form 100 trillion connections. Brain cells speak to each other by releasing chemicals into a small area known as the synapse, and...

Since 2021, The Erika Legacy Foundation has been generously supporting a range of innovative mental health research projects through Brain Canada. Their giving is inspired by Erika, who died by suicide in 2015. The unexpected death rocked her family—and galvanized them. Voices of Impact: The Erika...

Dr. Laura Donovan, Principal Investigator studying childhood cancer at Great Ormond Street Hospital in London, UK Brain cancer is the most common type of solid cancer in children, and can be notoriously difficult to target with interventions such as chemotherapy, radiation, or surgery. But the work...

Findings provide a treatment target and a starting point for new biomarke Read the full article here.

“We need to understand the fundamentals, we need to understand the underlying cell biology so that we can create good, rationally designed therapies.” – Dr. Christine Vande Velde “Everything started with a discovery we found by accident,” said Dr. Christine Vande Velde, a cellular biologist at the...

The exploration versus exploitation (E&E) decision making trade-off is something we experience every day. Project Overview The exploration versus exploitation (E&E) decision making trade-off is something we experience every day. Do I return to my favorite restaurant or try something new? Do I watch...

Thanks to Brain Canada, scientist Dr. Evdokia Anagnostou (right) does novel research that may lead to more targeted therapy for children with autism spectrum disorder. Some children with autism respond to certain treatments, and some don’t. Finding the right therapy depends on the particular...

There are many neurological and neuropsychiatric diseases that affect men and women differently, but we don’t have a clear picture as to why. One factor that may be important is the influence of hormones during puberty, which can change the way in which genes are used by brain cells, affecting their...

Michel Cayouette and his team are looking at whether the loss of cellular polarity could be a mechanism underlying multiple brain diseases, such as neurodegenerative diseases (like Alzheimer’s disease, stroke, and retinal degeneration), neuronal connectivity diseases (such as autism and...

Dr. Eran Hornstein (left) with Dr. Angela Genge Clinical trial evaluates the drug enoxacin as a therapeutic option for ALS, add-on studies supported by Discovery Grant "Ideally, one day, the results of our work will mean that we will be able to provide a new remedy for patients suffering from...