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Groundbreaking CHD research
https://braincanada.ca/about/news-updates/groundbreaking-chd-researchThree teams secure funding for groundbreaking congenital heart disease research Investigators will lead cutting edge research to support those living with CHD and their families Heart & Stroke, together with Brain Canada, the Canadian Institutes of Health Research (CIHR) Institute of Circulatory and...
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Groundbreaking research aims to reshape the future of advanced cancer
https://braincanada.ca/about/news-updates/groundbreaking-research-aims-to-reshape-the-future-of-advanced-cancerWith support from CCS and Brain Canada, three teams of experts are undertaking large-scale projects to change the lives of people affected by advanced cancer. It takes big ideas – and bold researchers – to help more people live well with and beyond advanced cancer. That’s why new grants announced...
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Gut Feeling: Two Breakthroughs for Understanding Parkinson’s and Its Progression Across the Body
https://braincanada.ca/about/news-updates/gut-feeling-two-breakthroughs-for-understanding-parkinson-s-and-its-progression-across-the-bodyResearchers in the Trudeau Lab. Skim through Brain Canada’s annual reports and you will spot the familiar face of Dr. Louis-Éric Trudeau. Dr. Trudeau led one of the five teams selected through the Brain Repair Program, launched in 2003, to pursue novel, paradigm-changing ideas. His team had two...
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Habitual physical activity, exercise and cardiovascular function in spinal cord injury
https://braincanada.ca/funded-grants/habitual-physical-activity-exercise-and-cardiovascular-function-in-spinal-cord-injuryThe major objectives of this research program are to measure the function of the heart and blood vessels following SCI and to investigate the mechanisms that are responsible for any changes that occur. Project Overview The major objectives of this research program are to measure the function of the...
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Harnessing beneficial aspects of neuroinflammation for regenerating the central nervous system
https://braincanada.ca/funded-grants/harnessing-beneficial-aspects-of-neuroinflammation-for-regenerating-the-central-nervous-systemThis research project, led by Dr. V. Wee Yong from the University of Calgary, focused on the immune system, which is comprised of two major components, the innate and adaptive systems. Innate immunity is the first immune component to sense and respond to an injury. Project Overview This research...
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Harnessing mRNA translation to increase the neuroprotective potential of disease-associated microglia in neurodegenerative diseases
https://braincanada.ca/funded-grants/harnessing-mrna-translation-to-increase-the-neuroprotective-potential-of-disease-associated-microglia-in-neurodegenerative-diseasesMicroglia are the brain’s immune cells. Project Overview Microglia are the brain’s immune cells. Research in recent years has revealed their crucial role in preventing the development of neurodegenerative diseases, including Alzheimer’s Disease (AD). However, the precise mechanisms by which...
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Health system implications of novel therapeutics for Alzheimer’s Disease: Supporting capacity planning with real-world evidence
https://braincanada.ca/funded-grants/health-system-implications-of-novel-therapeutics-for-alzheimer-s-disease-supporting-capacity-planning-with-real-world-evidenceClose to 600,000 Canadians currently live with Alzheimer’s disease and related dementias, but effective therapies are limited and focus on symptom management rather than a cure. Project Overview Close to 600,000 Canadians currently live with Alzheimer’s disease and related dementias, but effective...
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Help for kids with injured brains
https://braincanada.ca/about/news-updates/help-for-kids-with-injured-brainsDr. Freda Miller studies brain injury in children It was early 2010, and the research team in Dr. Freda Miller’s lab at the Hospital for Sick Children had just made an exciting discovery: they’d identified a crucial pathway for telling developing neural stem cells to make neurons and glia in the...
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HEMO Trial
https://braincanada.ca/funded-grants/hemo-trialSpinal cord injury (SCI) leads to dramatic alterations in physical and mental well-being. Project Overview Spinal cord injury (SCI) leads to dramatic alterations in physical and mental well-being. It is well understood that people with severe SCI lose their ability to move. However, a lesser-known...
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High-throughput single-cell optophysiology and RNA sequencing to understand seizure initiation and intervention
https://braincanada.ca/funded-grants/high-throughput-single-cell-optophysiology-and-rna-sequencing-to-understand-seizure-initiation-and-interventionEpilepsy – a brain disorder defined by repeated seizures – imposes significant challenges for individuals and society. Project Overview Epilepsy – a brain disorder defined by repeated seizures – imposes significant challenges for individuals and society. One of the most challenging cases of...