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Normal cells have a “self-cleaning” process called autophagy that breaks down and clears out cellular waste, so the cell can function properly. Project Overview Normal cells have a “self-cleaning” process called autophagy that breaks down and clears out cellular waste, so the cell can function...

Amyotrophic Lateral Sclerosis (ALS) is a fatal disease that damages nerve cells controlling movement, and many patients also experience major changes in how their bodies use energy. Project Overview Amyotrophic Lateral Sclerosis (ALS) is a fatal disease that damages nerve cells controlling...

Alzheimer’s Disease is a progressive and fatal disease that currently afflicts up to 400,000 Canadians over the age of 65. Project Overview Alzheimer’s Disease is a progressive and fatal disease that currently afflicts up to 400,000 Canadians over the age of 65. One key observation about this...

An understanding of emotional information from faces is critical for successful social interactions. Project Overview An understanding of emotional information from faces is critical for successful social interactions. A key component of ASD is poor social functioning. Deficits and dysfunction in...

While significant efforts have been made worldwide, the development of an effective therapy to significantly slow or halt amyotrophic lateral sclerosis (ALS) progression has remained elusive. Project Overview While significant efforts have been made worldwide, the development of an effective...

This project will determine the optimal intensity of reactive balance training (RBT) for people with chronic stroke. Project Overview This project will determine the optimal intensity of reactive balance training (RBT) for people with chronic stroke. More specifically, we will find the intensity...

To obtain a more inclusive understanding of vascular contributions to cognitive impairment and dementia (VCID) in women, we will investigate the relationship between vascular health and cognition in women belonging to Canada’s three largest ethnic groups (South Asian, Chinese, and White). Project...

Using the mirror image of body’s main sugar glucose (so-called L-glucose), we plan to hijack the sugar addiction of glioblastoma (GBM) as a therapeutic target. Project Overview Using the mirror image of body’s main sugar glucose (so-called L-glucose), we plan to hijack the sugar addiction of...

Most brain disorders remain incurable, whether they begin during early development, as seen in Autism, or seem acquired over time, as observed in Alzheimer’s disease. Project Overview Most brain disorders remain incurable, whether they begin during early development, as seen in Autism, or seem...

CHCHD10 is a nuclear encoded mitochondrial protein of the twin Cx9C family whose cellular function remains to be fully understood. Project Overview CHCHD10 is a nuclear encoded mitochondrial protein of the twin Cx9C family whose cellular function remains to be fully understood. Several dominantly...