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Depression is a leading cause of disability, with a large proportion of treatment-resistant patients. Recent studies have implicated reduced brain inhibition in human depression from a specific neuron type (SST), and new pharmacology boosting this reduced inhibition led to antidepressant and...

One percent of Alzheimer’s disease is the early-onset type that runs in families. Project Overview One percent of Alzheimer’s disease is the early-onset type that runs in families. Extensive studies of these ultra-rare forms of Alzheimer’s disease have revealed the genes that cause them. On the...

Roughly 10-20% of people self-report use of cannabis during pregnancy. Project Overview Canadian Consortium for the Investigation of Cannabinoids (CCIC) Neuroscience Fellowship in Cannabis and Cannabinoid Research Roughly 10-20% of people self-report use of cannabis during pregnancy. Human studies...

The highest lifetime risk of stroke is the week surrounding birth, with perinatal arterial ischemic stroke (AIS) the most common stroke subtype during this period. The highest lifetime risk of stroke is the week surrounding birth, with perinatal arterial ischemic stroke (AIS) the most common stroke...

There are many neurological and neuropsychiatric diseases that affect men and women differently, and the reasons for this are not well understood. Project Overview There are many neurological and neuropsychiatric diseases that affect men and women differently, and the reasons for this are not well...

Subcellular compartmentalization between the nucleus and cytoplasm is primarily governed by two systems; 1) active nucleocytoplasmic transport (NCT) regulated by Ran-GTPase and involving nuclear transport receptors such as Importin β-1, and 2) macromolecular nuclear pore complexes (NPCs) Project...

Early childhood is a critical stage of development. The things we learn and experience at this time set the stage for our later success and fundamentally shape us as people. It is clear that past and present colonial realities have given way to disruptions in parenting and traditional child-rearing...

Early childhood is a critical stage of development. The things we learn and experience at this time set the stage for our later success and fundamentally shape us as people. It is clear that past and present colonial realities have given way to disruptions in parenting and traditional child-rearing...

Meet the students who received the 2022 ALS Canada – Brain Canada Doctoral Awards. PhD student Lucia Meng Qi Jadon (previously Liao) is the recipient of a $75,000 ALS Canada – Brain Canada 2022 Trainee Award. She will use the funding to investigate whether a newly discovered tag on TDP-43 might have...

Huntington disease (HD) is an inherited disorder that causes brain cells to die and impacts approximately 1 in 7000 Canadians. Project Overview Huntington disease (HD) is an inherited disorder that causes brain cells to die and impacts approximately 1 in 7000 Canadians. A person with HD experiences...