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Personalized therapies are not yet a reality for children with medulloblastoma, a highly aggressive form of brain cancer. Treatment involves invasive surgery, radiation to the whole brain and spinal cord, and high doses of chemotherapy. Not only does this approach not cure all patients – the...

Complex research questions in neurology are often most effectively addressed by monitoring brain structure and function in human patients and live animals in experimental disease models. Project Overview Complex research questions in neurology are often most effectively addressed by monitoring...

Medulloblastoma isthe most common brain cancer in children. Project Overview Medulloblastoma isthe most common brain cancer in children. The current treatment for it includestoxic chemotherapy drugs which leadsto severe long-term side effectslike cognitive impairment. Still, the treatment failsfor...

The brain is more than the sum of its parts. Project Overview The brain is more than the sum of its parts. Truly understanding the brain’s most intricate properties requires both a list of its individual parts, that is a census of the types of neurons it contains, and a map of how these parts are...

The brain is an incredibly complex organ. Much of the brain’s complexity may be attributed to the circuitry that resides within. Project Overview The brain is an incredibly complex organ. Much of the brain’s complexity may be attributed to the circuitry that resides within. Synaptic connections are...

Maternal depression, particularly during pregnancy, has been well established as a risk factor for child socio-emotional problems. Project Overview Maternal depression, particularly during pregnancy, has been well established as a risk factor for child socio-emotional problems. However, the impact...

There are an increasing number of people living with dementia. Project Overview There are an increasing number of people living with dementia. Improving and maintaining quality of life is rated as the highest priority for people living with dementia and their caregivers. While many factors...

In developed countries, brain tumors are the leading cause of disability and death among children. Project Overview In developed countries, brain tumors are the leading cause of disability and death among children. Treatment advances have improved survival rates, but survival comes at a cost for...

Stroke is a major cause of death and disability. At present, there are no clear and effective therapies to aid the majority of patients who suffer stroke. Project Overview Stroke is a major cause of death and disability. At present, there are no clear and effective therapies to aid the majority of...

Focused ultrasound (FUS) is a non-invasive, ground-breaking technique suggested for the treatment of Alzheimer’s disease (AD). Project Overview Focused ultrasound (FUS) is a non-invasive, ground-breaking technique suggested for the treatment of Alzheimer’s disease (AD). The partners of the...