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Brain cancer is the most common type of solid cancer in children in Canada, and medulloblastoma is the most common malignant brain cancer of childhood. Project Overview Brain cancer is the most common type of solid cancer in children in Canada, and medulloblastoma is the most common malignant brain...

Pediatric high-grade gliomas are incurable brain cancers. Project Overview Pediatric high-grade gliomas are incurable brain cancers. Sequencing the tumor specimens has shown that most cases do not have obvious mutations that are known to cause cancer. It is therefore not known what causes, or...

Amyotrophic lateral sclerosis (ALS) is marked by dysfunction and degeneration of neuromuscular junctions (NMJ). Project Overview Amyotrophic lateral sclerosis (ALS) is marked by dysfunction and degeneration of neuromuscular junctions (NMJ). This can be one of the earliest pathological processes...

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterised by the loss of motor neurons and the atrophy of muscles. Project Overview Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterised by the loss of motor neurons and the atrophy of...

PHOTO: Momentum Grant recipients (from left): Annie Ciernia, Michèle Desjardins, Mark Cembrowski, Stuart Trenholm and Mark Brandon. Brain Canada is proud to announce the five recipients of the Momentum Grants, a new program that enables researchers to build upon their previously funded Future...

In this study, we. aim to do two things: 1) monitor the distribution of a-Syn in Parkinson’s disease (PD) context to understand the factors that can cause a-Syn to build-up in certain cells of the brain, called microglia. Project Overview In this study, we. aim to do two things: 1) monitor the...

Dr. Shmuel and his team are establishing a local platform which will support functional MRI (fMRI) in the alert non-human primate brain. Project Overview Dr. Shmuel and his team are establishing a local platform which will support functional MRI (fMRI) in the alert non-human primate brain. The...

Autism spectrum disorders (ASD) and schizophrenia (SZ) are two psychiatric conditions that affect approximately 2% of the general population. Genetic studies have identified mutations in hundreds of genes associated with ASD and SZ. Project Overview Autism spectrum disorders (ASD) and schizophrenia...

The project provides state of the art mouse brain imaging to researchers in Canada working on models of neurodevelopmental disorders. Project Overview The project provides state of the art mouse brain imaging to researchers in Canada working on models of neurodevelopmental disorders. The use of...

Neurodegenerative conditions such as Alzheimer’s and Parkinson’s disease profoundly affect aspects of cognition including memory Project Overview Neurodegenerative conditions such as Alzheimer’s and Parkinson’s disease profoundly affect aspects of cognition including memory, attention, decision...