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ALS is a devastating neurological disease characterized by the progressive degeneration of motor neurons leading to paralysis and death. Project Overview ALS is a devastating neurological disease characterized by the progressive degeneration of motor neurons leading to paralysis and death....

Individuals with Alzheimer’s suffer severe memory loss over time, and eventually are completely dependent on caregivers. Project Overview Individuals with Alzheimer’s suffer severe memory loss over time, and eventually are completely dependent on caregivers. Age is a significant risk factor, and...

Communication between brain cells is essential for normal brain function. Project Overview Communication between brain cells is essential for normal brain function. Healthy brain cells are controlled through chemical messengers that stimulate or inhibit brain activity. Current theories indicate...

Dr David Stojdl’s lab has custom‑built an oncolytic virus biotherapy specifically for the treatment of the devastating brain cancer, glioblastoma multiforme (GBM). Project Overview Dr David Stojdl’s lab has custom‑built an oncolytic virus biotherapy specifically for the treatment of the devastating...

A Brain Canada-funded platform is enabling new technology for drug discovery, in order to address a wide range of brain diseases and disorders: from epilepsy to autism, and brain tumors to ALS.  Bringing “One Brain” research to market for better brain health Dr. Kurrasch and colleague Dr. Deepika...

Working memory is our ability “keep in mind” information and manipulate it when it is not present in the environment. Project Overview Working memory is our ability “keep in mind” information and manipulate it when it is not present in the environment. It is central to many aspects of cognition,...

New funding to support early-career investigators committed to improving brain health for all Brain Canada is pleased to announce the launch of the 2023 Future Leaders in Canadian Brain Research program. The Future Leaders in Canadian Brain Research Program provides essential seed funding to assist...

When Dr. Monica Seger was 25, she received a grant to do a postdoctoral fellowship in the Netherlands. It was an experience that changed the trajectory of her life and research. As a young neuroendocrinologist, Monica benefited immensely from collaborating with scientists in a different culture. ...

Project Overview Major depression is among the most common and most burdensome human diseases worldwide. While there are several existing treatments, overall current treatments are modest in their efficacy. Over the past few decades, there has been significant development in the field of...

"Antisense oligonucleotides (ASOs) are synthetic single-stranded DNA/RNA that are useful in the targeting of mRNA sequences." Project Overview “Antisense oligonucleotides (ASOs) are synthetic single-stranded DNA/RNA that are useful in the targeting of mRNA sequences. Their versatility allows them...