Subventions financées

Research studies help us understand neurological health and develop better treatments; however, traditional research is often too slow, too expensive, and excludes people who live far from cities or face systemic barriers. ResearchAlly is changing that.

Innovative methods that enable brain-derived proteins to be measured in blood samples are transforming the field of neurology. For example, it is now possible to use a blood test to help diagnose Alzheimer’s Disease and to monitor treatment in Multiple Sclerosis. This project will establish The University of British Columbia (UBC) Platform for Neurology Biomarker Innovation (PNBI).

Therapeutic breakthroughs in Huntington Disease (HD), Alzheimer’s Disease (AD), Parkinson Disease (PD), and other neurodegenerative disorders have been accelerated by access to generously donated human samples. The HD Biobank at the University of British Columbia focuses on neurodegenerative disorders and is a leader in the collection of HD samples globally.

Amyotrophic Lateral Sclerosis (ALS) is a fatal disease that damages nerve cells controlling movement, and many patients also experience major changes in how their bodies use energy.

Contribution of stress-associated neurovascular alterations in Parkinson’s disease and high rates of depression

Investigating the role of EPG5 in Parkinson’s Disease pathogenesis

Amirhossein Jahani, a Postdoctoral Fellow at the University of Montreal, uses intracranial EEG to investigate how network interactions during the preictal phase (i.e., period preceding a seizure) may contribute to seizure initiation and propagation.

Impairments in social cognition (SC), such as difficulties in understanding emotions, social cues, and maintaining meaningful interactions, are key contributors to the loss of social inclusion and quality of life in individuals with neurodegenerative diseases (ND).

Jenna Hanrahan, a Doctoral Student at Memorial University of Newfoundland, aims to characterize the brain of a humanized mouse model of Huntington’s disease.

Using the mirror image of body’s main sugar glucose (so-called L-glucose), we plan to hijack the sugar addiction of glioblastoma (GBM) as a therapeutic target.