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889 results found

Enhancing Supports for Autistic Post-Secondary Students at the University of Calgary

Autistic individuals are disproportionately under-represented in post-secondary institutions, with only 35% of students with autism pursuing post-secondary education.


Grant type
Capacity building grants
Area of Research
Neurodevelopment
Competition
KBHN Early Career Investigator & Mentorship Awards
Province
Alberta
Start Date
2022

The development of an online peer navigation intervention for youth with neurodevelopmental disabilities

Background: Transition from the pediatric to adult health care system is a multi-faceted process that should include medical and psychosocial considerations.


Grant type
Capacity building grants
Area of Research
Neurodevelopment
Competition
KBHN Early Career Investigator & Mentorship Awards
Province
Ontario
Start Date
2022

Selectively Targeting ERK Signaling to Treat Fragile X Syndrome and Autism

Autism is one of the most prevalent neurodevelopmental disorders in Canada. It has a profound impact on the health, wellness and socioeconomic wellbeing of the patients and their families.


Grant type
Capacity building grants
Area of Research
Neurodevelopment
Competition
KBHN Early Career Investigator & Mentorship Awards
Province
Alberta
Start Date
2022

BCi-Move: Empowering severely disabled children to achieve power mobility with brain-computer interfaces (BCIs)

Thousands of Canadian children living with severe physical disability are intellectually capable but unable to move independently.


Grant type
Team grants
Area of Research
Neurodevelopment
Competition
KBHN Strategic Investment Fund
Province
Alberta
Start Date
2022

Community implementation and evaluation of acceptance and commitment training (ACT) for family caregivers

Family caregivers of people with neurodevelopmental disabilities (NDDs) often experience stress and mental health difficulties (e.g., anxiety, depression)


Grant type
Team grants
Area of Research
Neurodevelopment
Competition
KBHN Strategic Investment Fund
Province
Ontario
Start Date
2022

Neuronal reprogramming as a novel therapeutic strategy to treat Amyotrophic lateral sclerosis

The demonstration that mature somatic cells can be converted to new, heterologous cell types, now termed “cellular reprogramming”, led to the 2012 Nobel Prize in Physiology or Medicine, and sparked an explosion of studies investigating the therapeutic potential of such an approach.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Trainee Program 2022
Province
Ontario
Start Date
2022

Aberrant tRNA function exacerbates TDP-43 misfolding and toxicity in cellular models of ALS

Aberrant tRNA processing and function has the capacity to exacerbate misfolding of ALS-associated proteins and the ensuing toxicity.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Trainee Program 2022
Province
Ontario
Start Date
2022

Elucidating the role of stress granules dynamics in the pathogenesis of ALS

The lifetime risk of developing amyotrophic lateral sclerosis (ALS) is approximately 1 in 350 for men and 1 in 440 for women, making it the most common adult-onset motor neuron disease.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Trainee Program 2022
Province
Ontario
Start Date
2022

Quantitative PET/MR Imaging of Brain Derived Neurotrophic Factor (BDNF) / Tropomyosin Related Kinase B (TRKB) signaling in ALS – decoding a potential pathogenetic pathway

Brain derived neurotrophic factor (BDNF) is well recognized for its neuroprotective functions, via activation of its high affinity receptor, tropomysin related kinase B (TrkB).


Grant type
Team grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Alberta
Start Date
2022

Investigating TDP-43 palmitoylation as a therapeutic target to lower protein aggregation

TDP-43 (transactive response DNA-binding protein 43) is one of the few genes highly associated with ALS (amyotrophic lateral sclerosis).


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Trainee Program 2022
Province
Ontario
Start Date
2022