Funded Grants

Mutations in the SOD1 gene, leading to the misfolding and toxic aggregation of SOD1 protein, are the second leading cause of Familial Amyotrophic Lateral Sclerosis (FALS-SOD1) and emerging literature has detected misfolded SOD1 (mSOD1) in the cerebrospinal fluid (CSF) and post-mortem tissue of Sporadic ALS (SALS) patients.

Stroke is a common and disabling brain disorder which may have long-lasting effects.

Because of low fitness and heart problems, people with stroke are at very high risk of a second stroke or heart attack within 10 years.

The first question people ask after suffering a stroke is: “Why?”

One in four strokes are caused by a condition called cerebral small vessel disease (CSVD). There are no approved treatments for CSVD.

We are testing a new digital mental health solution for physicians to better manage the treatment of depression.

While significant efforts have been made worldwide, the development of an effective therapy to significantly slow or halt amyotrophic lateral sclerosis (ALS) progression has remained elusive.

TDP-43 is an essential DNA/RNA binding protein at the epicenter of Amyotrophic Lateral Sclerosis (ALS).

Current biomarkers of ALS used by clinicians to help care for ALS patients have many drawbacks that may include cost, accessibility, and invasiveness of procedures.

Ischemic stroke occurs when a person suffers a sudden blockage of an artery in their brain.