Funded Grants

The early and severe loss of serotonin neurons along with the neuroprotective effects of SSRIs in Alzheimer’s Disease (AD) strongly implicates the serotonin system in disease pathology.

Our project proposes the development and first-step validation of a new, noninvasive mapping procedure of proteinopathy in asymptomatic older adults.

Many people with dementia (PwD) live in nursing homes, which often suffer from a lack of skilled staff to support and monitor the safety of residents.

Among the earliest signs of preclinical Alzheimer’s disease (AD) are navigation impairments and the presence of abnormal Tau (aTau) proteins in the entorhinal cortex (EC), a brain region that represents space and movement.

Trans women may take estradiol-based gender affirming hormone therapy (GAHT) into their old age.

Age is the most important risk factor for Parkinson’s Disease (PD), followed by sex, with a higher risk in males.

Dr. Tang and her team at the University of British Columbia will use a virtual care platform to deliver peer-led mental health support to rural and remote communities in BC, through an intervention called REACHOUT, created with support from a previous JDRF grant.

A G4C2 repeat expansion in C9orf72 (chromosome 9 open reading frame 72), a gene of unclear function, is the most frequent genetic cause of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (C9-ALS/FTD).

Amyotrophic lateral sclerosis (ALS) is a debilitating and terminal disease.