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839 results found

Defining conserved functions of RNA binding proteins in stress-granule biogenesis

RNA is a mobile form of genetic information that is made from our DNA and its complex regulation is extremely important to the proper functioning of our cells.


Grant type
Team grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2017

Integrative discovery of ion channels as drug targets in glioblastoma

Ion channel (IC) proteins are known to be involved in different human diseases such as heart and brain disorders.


Grant type
Team grants
Area of Research
Cancer
Competition
Canadian Cancer Society Innovation Grants
Province
Ontario
Start Date
2017

Impaired Neuromuscular Junction Connectivity in Amyotrophic Lateral Sclerosis

Many scientists believe that one of the earliest abnormalities in ALS is dysfunction at the place where motor neurons connect to muscle, known as the neuromuscular junction (NMJ).


Grant type
Team grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Discovery Grants
Province
British Columbia
Start Date
2017

Sleep, cognition, and inflammation following natural or surgical menopause

Alzheimer’s disease disproportionately affects women and emerging evidence suggests there may be unique biological and lifestyle factors that underlie these differences.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Alzheimer's Association Research Fellowship
Province
Ontario
Start Date
2017

Montreal integrated neuropsychiatric cohort: Identifying subtypes of Autism and Schizophrenia integrating genomics, endophenotypes, and cohorts of high-risk genetic variants

Autism spectrum disorders (ASD) and schizophrenia (SZ) are two psychiatric conditions that affect approximately 2% of the general population. Genetic studies have identified mutations in hundreds of genes associated with ASD and SZ.


Grant type
Team grants
Area of Research
Multiple
Competition
2015 MIRI Team Grants
Province
Québec
Start Date
2017

Combining neurostimulation technique with tailored interventions for the affected upper extremity: can it promote better recovery in stroke survivors?

A substantial proportion of individuals are left with poor residual functioning of the affected arm after a stroke.


Grant type
Team grants
Area of Research
Injury
Competition
2015 MIRI Team Grants
Province
Québec
Start Date
2017

The Aging Brain: Circadian, Transcriptomic, and Epigenomic Dimensions

One of the most important questions of biomedical research is “why do we ail as we age?”.


Grant type
Team grants
Area of Research
Neurodegeneration
Competition
2015 MIRI Team Grants
Province
Ontario
Start Date
2017

Development and validation of reagent kits for commercial high-throughput screening of PPI s and PPI inhibitors

Membrane proteins are biological molecules of incredible importance, playing diverse roles in many processes critical to life.


Grant type
Platform grants
Area of Research
Neurotechnology
Competition
CQDM - Brain Canada - Quantum Leap
Province
Ontario
Start Date
2017

Mechanisms of glutamatergic neuronal dysfunction in genetic models of ALS

This project will focus on comprehensively studying impaired transmission of signals (from the brain) at the location where neurons and muscles meet, called the neuromuscular junction.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Career Transition Award
Province
Québec
Start Date
2017

Pathogenic mechanisms of C9ORF72 repeat expansion in ALS and development of therapeutics

Dr. Patten started his research career as a PhD student at the University of Alberta under the supervision of Dr. Declan Ali in 2004.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Career Transition Award
Province
Québec
Start Date
2017