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853 results found

Molecular characterization of transcriptional repressor capicua in GBM

Malignant gliomas, including oligodendrogliomas (OD) and glioblastomas (GBM), are currently incurable brain tumours with few effective treatment options.


Grant type
Team grants
Area of Research
Cancer
Competition
Canadian Cancer Society Innovation Grants
Province
Ontario
Start Date
2017

Using synthetic antibody parts to construct antibody-based imaging devices – anti-EGFR molecular targeted imaging probes for diagnosing and monitoring glioblastoma

To improve outcomes in brain cancer, better tools are needed to diagnose brain cancer, surgically remove brain tumours and monitor how they respond to therapy.


Grant type
Team grants
Area of Research
Cancer
Competition
Canadian Cancer Society Innovation Grants
Province
Saskatchewan
Start Date
2017

Montreal integrated neuropsychiatric cohort: Identifying subtypes of Autism and Schizophrenia integrating genomics, endophenotypes, and cohorts of high-risk genetic variants

Autism spectrum disorders (ASD) and schizophrenia (SZ) are two psychiatric conditions that affect approximately 2% of the general population. Genetic studies have identified mutations in hundreds of genes associated with ASD and SZ.


Grant type
Team grants
Area of Research
Multiple
Competition
2015 MIRI Team Grants
Province
Québec
Start Date
2017

Combining neurostimulation technique with tailored interventions for the affected upper extremity: can it promote better recovery in stroke survivors?

A substantial proportion of individuals are left with poor residual functioning of the affected arm after a stroke.


Grant type
Team grants
Area of Research
Injury
Competition
2015 MIRI Team Grants
Province
Québec
Start Date
2017

The Aging Brain: Circadian, Transcriptomic, and Epigenomic Dimensions

One of the most important questions of biomedical research is “why do we ail as we age?”.


Grant type
Team grants
Area of Research
Neurodegeneration
Competition
2015 MIRI Team Grants
Province
Ontario
Start Date
2017

Testing therapeutic approaches to improve cognitive dysfunction in a primate model of Alzheimer’s Disease

Alzheimer’s Disease (AD) is a severe dementia that is likely a result of years of buildup in the brain of molecules called amyloid-beta oligomers (AβOs).


Grant type
Team grants
Area of Research
Neurodegeneration
Competition
2015 MIRI Team Grants
Province
Ontario
Start Date
2016

The role of attention control and emotional regulation in the emergence of autism spectrum disorder (ASD): Identifying early behavioral markers of ASD in at-risk infants

Ms. Raza’s research focuses on early development in autism spectrum disorder (ASD), with the goal of identifying behavioral and physiological markers in at-risk infants.


Grant type
Capacity building grants
Area of Research
Neurodevlopment
Competition
Brain Canada - Kids Brain Health Network Training Awards
Province
Alberta
Start Date
2016

In vitro and in vivo functional assessment of neuropsychiatric disease-related synaptic gene mutations

Dr. Xie’s research focuses on the functional assessment of neuropsychiatric disease related synaptic genes – MDGA1 and 2. MDGAs bind to critical neuron synaptic proteins – Neuroglin (NLGN), disrupting the binding between NLGN and Neurexin (NRXN), so suppressing synaptogenesis.


Grant type
Capacity building grants
Area of Research
Multiple
Competition
Brain Canada - Kids Brain Health Network Training Awards
Province
British Columbia
Start Date
2016

Mouse brain imaging for neurodevelopmental disorders

The project provides state of the art mouse brain imaging to researchers in Canada working on models of neurodevelopmental disorders.


Grant type
Team grants
Area of Research
Neurodevlopment
Competition
Azrieli Neurodevelopment Research Program
Province
Ontario
Start Date
2016

2016 Dr. Hubert van Tol Travel Fellowship

The overarching aim of Ms Morena’s research is to investigate the role of the endocannabinoid system in the modulation of memory processes and its interaction with stress and emotional arousal in animal models of cognition, at a cellular, circuit and behavioural level.


Grant type
Capacity building grants
Area of Research
Mental Health
Competition
Dr. Hubert van Tol Travel Fellowship
Province
Alberta
Start Date
2016