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839 results found

A national coordinating neuroinformatics framework for autism and related conditions

New approaches in neurodevelopmental research increasingly seek to integrate enormous amounts of data through sophisticated informatics so as to determine the relationship between genotype and phenotypes, both structural and functional, as they change over time during development.


Grant type
Team grants
Area of Research
Neurodevlopment
Competition
Azrieli Neurodevelopment Research Program
Province
Québec
Start Date
2016

Summer School in Computational Sensory Motor Neuroscience (CoSMo)

Major breakthroughs in neuroscience have been achieved through the application of computational models to empirical research.


Grant type
Capacity building grants
Area of Research
Neurotechnology
Competition
BRAIN Initiative
Province
Ontario
Start Date
2016

Testing therapeutic approaches to improve cognitive dysfunction in a primate model of Alzheimer’s Disease

Alzheimer’s Disease (AD) is a severe dementia that is likely a result of years of buildup in the brain of molecules called amyloid-beta oligomers (AβOs).


Grant type
Team grants
Area of Research
Neurodegeneration
Competition
2015 MIRI Team Grants
Province
Ontario
Start Date
2016

Novel approaches to early detection and treatment of ASD

More than 1 in 100 individuals are diagnosed with Autism Spectrum Disorder (ASD), with profound impacts on the quality of life of those who are affected and their families.


Grant type
Team grants
Area of Research
Neurodevlopment
Competition
Azrieli Neurodevelopment Research Program
Province
Alberta
Start Date
2016

A Patient-Derived hiPSC Neuronal Platform for Drug Discovery in Parkinson’s Disease and Amyotrophic Lateral Sclerosis

Parkinson’s Disease (PD) and Amyotrophic Lateral Sclerosis (ALS) are two of the most common and devastating neurodegenerative diseases, affecting more than 2% of the population over the age of 65.


Grant type
Platform grants
Area of Research
Neurodegeneration
Competition
CQDM - Brain Canada - Focus on Brain
Province
Québec
Start Date
2016

Novel approaches to understand the role of cAMP and co-signaling cascades in synaptic plasticity and brain disorders

Synaptic plasticity is the process where the strength of connections between nerve cells is altered by experience.


Grant type
Team grants
Area of Research
Central Nervous System
Competition
2015 MIRI Team Grants
Province
Ontario
Start Date
2016

ShARP: Screenable assays for RNA-binding proteins involved in brain disorders and diseases

Brain disorders such as autism, major depressive disorder and Alzheimer’s disease are among the greatest medical challenges of our era.


Grant type
Platform grants
Area of Research
Neurotechnology
Competition
CQDM - Brain Canada - Focus on Brain
Province
Ontario
Start Date
2016

Tracking Alzheimer’s disease progression at the earliest stages: a multimodal project

New neuroimaging techniques enable us to measure the key hallmarks of Alzheimer’s disease (AD) pathology before symptoms appear.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Alzheimer's Society Research Program (ASRP)/Brain Canada New Investigator & Career Change Grants
Province
Québec
Start Date
2016

Role of mitochondrial c-Src kinase in Alzheimer’s disease

Mitochondrial dysfunctions are observed before and during the progression of Alzheimer’s disease (AD).


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Alzheimer's Society Research Program (ASRP)/Brain Canada New Investigator & Career Change Grants
Province
New Brunswick
Start Date
2016

Novel mechanisms regulating intraneuronal Tau clearance as potential targets for Alzheimer’s disease

In Alzheimer’s disease (AD), the accumulation of toxic Tau protein in neurons leads to the formation of neurofbillary tangles, cell death, and cognitive impairments.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Alzheimer's Society Research Program (ASRP)/Brain Canada New Investigator & Career Change Grants
Province
Québec
Start Date
2016