Funded Grants

In some cases of ALS, it is clear that specific inherited genetic changes (called mutations) can not only cause the disease, but can do so by creating a protein (the end product of genes that actually does a function in our cells) that has an abnormal, toxic function resulting in motor neuron degeneration.

In ALS, the disease is characterized by degeneration of motor neurons and an inability of the brain to signal the muscles to move, resulting in paralysis.

The first genetic cause of ALS to be discovered (in 1993) encoded a mutation in protein called superoxide dismutase 1 (SOD1).

Dr. David and his research team are studying the mechanisms that control the delivery and release of iron in the nervous system.

Adolescence represents a unique developmental window of the life cycle to adopt healthy behaviours that will support psychosocial adjustment and well-being during adolescence and adulthood (World Health Organization, 2001).

Dr. Shmuel and his team are establishing a local platform which will support functional MRI (fMRI) in the alert non-human primate brain.

The Centre for Functional and Metabolic Mapping (CFMM) at Western’s Robarts Research Institute houses Canada’s only collection of high-field (3T human) and ultra-high field (7T human and 9.4T animal) MR systems.

The Toronto Dementia Research Alliance will establish a clinical research platform that will provide a consistent and efficient approach to managing research and clinical care in patients with neurodegenerative conditions.

The proposed initiative will make every brain tumour count!

Advances in neuroimaging over the past several years have provided researchers with unprecedented access into the inner workings of the brain.