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Radiomics and machine learning based non-invasive biomarkers for prediction of peritumoral invasion in brain metastases
https://braincanada.ca/funded-grants/radiomics-and-machine-learning-based-non-invasive-biomarkers-for-prediction-of-peritumoral-invasion-in-brain-metastasesNeed for project: Treatment of brain metastases (BrM) includes a combination of surgery and radiation therapy (RT). Project Overview Need for project: Treatment of brain metastases (BrM) includes a combination of surgery and radiation therapy (RT). Recurrence after treatment is a problem that...
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Rational targeting of FUS and TDP-43 protein assemblies for diagnostics and treatment of ALS
https://braincanada.ca/funded-grants/rational-targeting-of-fus-and-tdp-43-protein-assemblies-for-diagnostics-and-treatment-of-alsThe project addresses a grand challenge in ALS, the integration of a multi-targeted and personalized approach to patients with a rational strategy focusing on a unifying pivotal mechanism of the disease. Project Overview The project addresses a grand challenge in ALS, the integration of a...
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RBC Disruptors – Rewiring the Brain
https://braincanada.ca/about/news-updates/rbc-disruptors-rewiring-the-brainTechnology is disrupting the brain. Dr. Murali Doraiswamy, a physician and brain scientist at Duke University highlighted that 8%-10% of people in North America show signs of a serious addiction to the Internet and gaming – on this special episode we turned our minds inward – Murali shares his...
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RBC Foundation donates $2 million to help launch first-ever Brain Canada Youth Mental Health Platform
https://braincanada.ca/about/news-updates/rbc-foundation-donates-2-million-to-help-launch-first-ever-brain-canada-youth-mental-health-platformThe toll of the COVID-19 pandemic on young people’s collective mental health and wellness has been massive. Mental illness disproportionately affects people between the ages of 15 and 29 worldwide, and accounts for approximately half of the overall burden of disease in this age group, making it the...
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Read the latest issue of WBHI’s Mind Over Matter Magazine
https://braincanada.ca/about/news-updates/read-the-latest-issue-of-wbhi-s-mind-over-matter-magazineRead the latest edition of Mind Over Matter magazine, published by the Women’s Brain Health Initiative, in partnership with Brain Canada. This issue includes an inspiring story on Brain Canada-funded researcher Dr. Nathalie Bier and her work to help people with Alzheimer’s continue to cook for...
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Real-life recall: An fMRI exploration of episodic memory in the real-world
https://braincanada.ca/funded-grants/real-life-recall-an-fmri-exploration-of-episodic-memory-in-the-real-worldMemory is a fundamental aspect of human cognition that allows us to remember past experiences that shape our future actions. Project Overview Memory is a fundamental aspect of human cognition that allows us to remember past experiences that shape our future actions. However, disorders such as...
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Recruitment of Endogenous Neural Stem Cells to Promote Brain Repair Following Acquired Brain Injury in Children
https://braincanada.ca/funded-grants/recruitment-of-endogenous-neural-stem-cells-to-promote-brain-repair-following-acquired-brain-injury-in-childrenIn Canada, over 140,000 children and teenagers suffer a brain injury each year due to trauma, stroke, cerebral palsy, and brain cancer. Project Overview In Canada, over 140,000 children and teenagers suffer a brain injury each year due to trauma, stroke, cerebral palsy, and brain cancer. Children...
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Regeneration Unit in Neurology: A platform for research and training in advanced microscopy and behavioural approaches
https://braincanada.ca/funded-grants/regeneration-unit-in-neurology-a-platform-for-research-and-training-in-advanced-microscopy-and-behavioural-approachesThe Regeneration Unit in Neurobiology (RUN) Core facility is a purpose-built centre specializing in state of the art microscopic imaging of cells and tissue, as well as sophisticated behavioural analysis of laboratory rodents. Project Overview The Regeneration Unit in Neurobiology (RUN) Core...
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Regulation of endosomal membrane trafficking by C9ORF72 in ALS
https://braincanada.ca/funded-grants/regulation-of-endosomal-membrane-trafficking-by-c9orf72-in-alsDr. Peter McPherson, professor at the Montreal Neurological Institute, McGill University will receive one year of support to work on the connection between the most prominent known cause of ALS, a mutation in a gene called C9ORF72, and a previously unrelated critical cellular function called...
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Regulation of the stress granule proteome and transcriptome by TDP-43 in ALS: biomarkers and therapeutic targets
https://braincanada.ca/funded-grants/regulation-of-the-stress-granule-proteome-and-transcriptome-by-tdp-43-in-als-biomarkers-and-therapeutic-targetsWhen cells are under stress, one of the reactions is to form tiny clumps called stress granules that protect important genetic information while protective mechanisms kick in. Project Overview When cells are under stress, one of the reactions is to form tiny clumps called stress granules that...