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Pushing boundaries in medical imaging to explore new pathways for ALS treatment
https://braincanada.ca/about/news-updates/pushing-boundaries-in-medical-imaging-to-explore-new-pathways-for-als-treatment“The idea is to not only diagnose but also to help in developing targeted treatments.” – Dr. Freimut Juengling Neurological imaging has advanced by leaps and bounds in the past two decades. Researchers can now “see” details of biological processes at a level never previously imagined. But we still...
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Pushing the boundaries of autism research
https://braincanada.ca/about/news-updates/pushing-the-boundaries-of-autism-research -
Quantitative fluorescence spectroscopy of the central nervous system amylome
https://braincanada.ca/funded-grants/quantitative-fluorescence-spectroscopy-of-the-central-nervous-system-amylomeIt is generally acknowledged that accumulation of misfolded proteins (amyloid) in brains of Alzheimer’s disease patients is a key disease phenomenon. Project Overview It is generally acknowledged that accumulation of misfolded proteins (amyloid) in brains of Alzheimer’s disease patients is a key...
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Quantitative MRI as a biomarker of tumour resistance to radiation treatment in brain metastasis
https://braincanada.ca/funded-grants/quantitative-mri-as-a-biomarker-of-tumour-resistance-to-radiation-treatment-in-brain-metastasisBrain metastasis occurs in 20% to 40% of all cancer patients and impacts quality of life and survival. Stereotactic radiosurgery (SRS), which involves delivering high doses of radiation to the tumour, is the preferred treatment for these patients. Project Overview Brain metastasis occurs in 20% to...
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Quantitative PET/MR Imaging of Brain Derived Neurotrophic Factor (BDNF) / Tropomyosin Related Kinase B (TRKB) signaling in ALS – decoding a potential pathogenetic pathway
https://braincanada.ca/funded-grants/quantitative-pet-mr-imaging-of-brain-derived-neurotrophic-factor-bdnf-tropomyosin-related-kinase-b-trkb-signaling-in-als-decoding-a-potential-pathogenetic-pathwayBrain derived neurotrophic factor (BDNF) is well recognized for its neuroprotective functions, via activation of its high affinity receptor, tropomysin related kinase B (TrkB). Project Overview Brain derived neurotrophic factor (BDNF) is well recognized for its neuroprotective functions, via...
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Radiomics and machine learning based non-invasive biomarkers for prediction of peritumoral invasion in brain metastases
https://braincanada.ca/funded-grants/radiomics-and-machine-learning-based-non-invasive-biomarkers-for-prediction-of-peritumoral-invasion-in-brain-metastasesNeed for project: Treatment of brain metastases (BrM) includes a combination of surgery and radiation therapy (RT). Project Overview Need for project: Treatment of brain metastases (BrM) includes a combination of surgery and radiation therapy (RT). Recurrence after treatment is a problem that...
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Rational targeting of FUS and TDP-43 protein assemblies for diagnostics and treatment of ALS
https://braincanada.ca/funded-grants/rational-targeting-of-fus-and-tdp-43-protein-assemblies-for-diagnostics-and-treatment-of-alsThe project addresses a grand challenge in ALS, the integration of a multi-targeted and personalized approach to patients with a rational strategy focusing on a unifying pivotal mechanism of the disease. Project Overview The project addresses a grand challenge in ALS, the integration of a...
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RBC Disruptors – Rewiring the Brain
https://braincanada.ca/about/news-updates/rbc-disruptors-rewiring-the-brainTechnology is disrupting the brain. Dr. Murali Doraiswamy, a physician and brain scientist at Duke University highlighted that 8%-10% of people in North America show signs of a serious addiction to the Internet and gaming – on this special episode we turned our minds inward – Murali shares his...
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RBC Foundation donates $2 million to help launch first-ever Brain Canada Youth Mental Health Platform
https://braincanada.ca/about/news-updates/rbc-foundation-donates-2-million-to-help-launch-first-ever-brain-canada-youth-mental-health-platformThe toll of the COVID-19 pandemic on young people’s collective mental health and wellness has been massive. Mental illness disproportionately affects people between the ages of 15 and 29 worldwide, and accounts for approximately half of the overall burden of disease in this age group, making it the...
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Read the latest issue of WBHI’s Mind Over Matter Magazine
https://braincanada.ca/about/news-updates/read-the-latest-issue-of-wbhi-s-mind-over-matter-magazineRead the latest edition of Mind Over Matter magazine, published by the Women’s Brain Health Initiative, in partnership with Brain Canada. This issue includes an inspiring story on Brain Canada-funded researcher Dr. Nathalie Bier and her work to help people with Alzheimer’s continue to cook for...