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Postpartum mental health problems, including depression and anxiety, affect 15-20% of people and are a serious public health concern. Project Overview Postpartum mental health problems, including depression and anxiety, affect 15-20% of people and are a serious public health concern. Untreated...

Neuroscience researchers at Western University have developed the first open-access repository for raw data from mouse cognitive testing. Called MouseBytes, the database gives researchers a platform to share rodent cognition data using touchscreen cognitive testing with labs around the world. It is...

Pictured here: Daniel Blumberger, Catherine Lebel, Martin Lepage, Manuela Ferrari, and Tarek Rajji are leading the research projects receiving funding from Bell Let’s Talk and Brain Canada Five Canadian research teams receive major grants to address gaps in mental health care highlighted by the...

The blood-brain barrier (BBB) plays an essential role in protecting the brain from blood-borne diseases. Project Overview The blood-brain barrier (BBB) plays an essential role in protecting the brain from blood-borne diseases. However, it blocks otherwise effective medicine from reaching the brain....

Mutations within exon 1 of the huntingtin (HTT) protein promote its aggregation and accumulation in the brain and periphery, ultimately driving neuronal dysfunction and the clinical manifestation of Huntington’s disease (HD). Although HTT is a large protein composed of more than 3,000 amino acids,...

Tammy Moore, Chief Executive Officer, ALS Canada, participating in the Ice Bucket Challenge. Remember the Ice Bucket Challenge? The frisson of being challenged. The chill of water cascading down a body. The issuing of a summons to a friend or family. All for a noble cause: to promote aware­ness and...

In 97 per cent of ALS cases and nearly half of cases of frontotemporal dementia, the TDP-43 protein is misplaced to an area outside the cell nucleus of the motor neuron called the cytoplasm. Project Overview In 97 per cent of ALS cases and nearly half of cases of frontotemporal dementia, the TDP-43...

In 2021 we reported on the progress of Dr. Mari DeMarco’s IMPACT-AD project funded in part by Brain Canada, which was evaluating the implementation of a comprehensive biomarker testing strategy for Alzheimer’s disease. Study confirms value of biomarker testing in dementia care Dr. Mari DeMarco and...

Each year, over 1,500 Canadians sustain an acute spinal cord injury (SCI), and join close to 40,000 across our nation living with one of the most physically and psychologically devastating of injuries. Project Overview Each year, over 1,500 Canadians sustain an acute spinal cord injury (SCI), and...

Moving neuroscience research from the lab and turning it into a product is extremely challenging. Even the most groundbreaking technologies may never improve a patient’s life if the commercialization path is not successfully navigated. Project Overview Moving neuroscience research from the lab and...