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Cortical GABAergic interneurons migration impairment in genetic epileptic encephalopathies
https://braincanada.ca/funded-grants/cortical-gabaergic-interneurons-migration-impairment-in-genetic-epileptic-encephalopathiesDr. Eid will test the hypothesis that the Trio gene is a central regulator of the development and maturation of cortical interneurons (INs) and that its loss underlies some genetic forms of epileptic encephalopathies (EE) by disrupting cortical network development and function. Project Overview Dr....
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Could a ketogenic diet slow the progression of ALS?
https://braincanada.ca/about/news-updates/could-a-ketogenic-diet-slow-the-progression-of-als“Increase your caloric intake.” This is the number one recommendation that a clinician will make to a person recently diagnosed with Amyotrophic Lateral Sclerosis (ALS), a neurodegenerative disease affecting nerve cells in the brain and spinal cord, causing loss of muscle control. A high calorie...
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Could inflammation in this pathway provide a new target for ALS therapies?
https://braincanada.ca/about/news-updates/could-inflammation-in-this-pathway-provide-a-new-target-for-als-therapiesDr. Honglin Luo (left) and Dr. Neil Cashman. Discovery Grant empowers Canadian team to examine the cGAS-STING pathway across a range of ALS models “The Discovery Grant is very crucial for us,” says Dr. Luo, “since it allows us to quickly look at the outcome.” Dr. Cashman also emphasizes speed as a...
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Could mindfulness improve quality of life for people living with ALS?
https://braincanada.ca/about/news-updates/could-mindfulness-improve-quality-of-life-for-people-living-with-alsDiscovery Grant will fuel an interdisciplinary mindfulness study for people living with ALS and their caregivers “Research suggests that being more mindful may allow people a greater sense of perceived control. This is doubly relevant because an ALS diagnosis can bring about elements of fear and...
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CQDM and Brain Canada Inject $1 M in Top BC Biotech Firm AbCellera to Advance Discovery Platform for Next-Generation Antibody Therapeutics
https://braincanada.ca/about/news-updates/cqdm-and-brain-canada-inject-1-m-in-top-bc-biotech-firm-abcellera-to-advance-discovery-platform-for-next-generation-antibody-therapeuticsThe program will leverage AbCellera’s high-throughput, single-cell screening platform to allow rapid identification of functional antibodies against complex membrane proteins. MONTREAL, January 12th, 2018– CQDM and Brain Canada are proud to announce the non-dilutive funding of $1 M to AbCellera and...
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CQDM, Brain Canada and industry partners join forces to address unmet medical needs
https://braincanada.ca/about/news-updates/cqdm-brain-canada-and-industry-partners-join-forces-to-address-unmet-medical-needsCQDM and Brain Canada are proud to announce the funding of three collaborative research projects, for a total of $7.4 million which includes financial support from various industry partners, aimed at addressing unmet needs in the treatment of brain disorders. These projects are made possible by a...
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CQDM, Healthy Brains for Healthy Lives (HBHL), Corbin Therapeutics and Brain Canada award $1.5 million to McGill Professor Philippe Gros who will pursue the development of new molecules to fight neuroinflammation
https://braincanada.ca/about/news-updates/cqdm-healthy-brains-for-healthy-lives-hbhl-corbin-therapeutics-and-brain-canada-award-1-5-million-to-mcgill-professor-philippe-gros-who-will-pursue-the-development-of-new-molecules-to-fight-neuroinflammationMontreal, May 2nd, 2019 – CQDM is pleased to announce that Professor Philippe Gros from McGill University has been awarded $1.5 million as part of the SynergiQC program to pursue the development and validation of new inhibitors of ubiquitin-specific protein protease (USP-15) and its partner TRIM25,...
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Creating computers that work like the human brain
https://braincanada.ca/about/news-updates/creating-computers-that-work-like-the-human-brainLearning in Machines and Brains Senior Fellow, Joëlle Pineau, presents at the December 2015 meeting of CIFAR’s program Learning in Machines and Brains Learning in Machines and Brains is one of the 14 global research programs at CIFAR (Canadian Institute For Advanced Research). The CIFAR research...
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Creating viruses that can shrink brain tumours
https://braincanada.ca/about/news-updates/creating-viruses-that-can-shrink-brain-tumoursBright flashes of green and yellow mark the spots where Farmington virus is killing susceptible target cells (red). David Stojdl and his team are trying a different way to treat brain tumours. Their lab has custom-built an oncolytic virus biotherapy specifically for the treatment of the devastating...
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CRF receptor-mediated sensitization of 5-HT2A receptor signalling
https://braincanada.ca/funded-grants/crf-receptor-mediated-sensitization-of-5-ht2a-receptor-signallingThe proposed research in this application will significantly broaden our understanding of the molecular basis for how stress leads to anxiety and depression. Project Overview The proposed research in this application will significantly broaden our understanding of the molecular basis for how stress...