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Defining conserved functions of RNA binding proteins in stress-granule biogenesis
https://braincanada.ca/funded-grants/defining-conserved-functions-of-rna-binding-proteins-in-stress-granule-biogenesisRNA is a mobile form of genetic information that is made from our DNA and its complex regulation is extremely important to the proper functioning of our cells. Project Overview RNA is a mobile form of genetic information that is made from our DNA and its complex regulation is extremely important to...
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Defining the role of primary cilia in shaping astrocyte development and response to brain insults
https://braincanada.ca/funded-grants/defining-the-role-of-primary-cilia-in-shaping-astrocyte-development-and-response-to-brain-insultsAstrocytes are a major type of cells that react to brain activity, injuries and diseases to help support optimal brain functions. Project Overview Astrocytes are a major type of cells that react to brain activity, injuries and diseases to help support optimal brain functions. It is increasingly...
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Dementia Talks! Canada
https://braincanada.ca/funded-grants/dementia-talks-canadaPartners and Donors Alzheimer Society of Canada
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Democratizing access to tools for innovation
https://braincanada.ca/about/news-updates/democratizing-access-to-tools-for-innovationImagine a neurosurgeon using light or sound to manipulate specific cells in your brain and restore your brain health. Instead of implanting electrodes and buzzing broader areas of your brain to help relieve symptoms of Parkinson’s disease, for example, a neurosurgeon would use gene therapy to...
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Design and Development of Analogues of beta-Alanine as Therapeutics for AD
https://braincanada.ca/funded-grants/design-and-development-of-analogues-of-beta-alanine-as-therapeutics-for-adWhen brain cells are injured during Alzheimer’s disease, those cells may either die or become too electrically excitable. Project Overview When brain cells are injured during Alzheimer’s disease, those cells may either die or become too electrically excitable. This study’s objective is to design...
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Designing synthetic extracellular matrices to support neurodegenerative disease modeling
https://braincanada.ca/funded-grants/designing-synthetic-extracellular-matrices-to-support-neurodegenerative-disease-modelingWe propose to develop chemically defined synthetic extracellular matrices to support neural cells in longterm stable cell culture. Project Overview We propose to develop chemically defined synthetic extracellular matrices to support neural cells in longterm stable cell culture. Human induced...
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Detecting Behaviours of Risk in Nursing Homes using Deep Learning
https://braincanada.ca/funded-grants/detecting-behaviours-of-risk-in-nursing-homes-using-deep-learningMany people with dementia (PwD) live in nursing homes, which often suffer from a lack of skilled staff to support and monitor the safety of residents. Project Overview Many people with dementia (PwD) live in nursing homes, which often suffer from a lack of skilled staff to support and monitor the...
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Detection and prevention of pypermutant glioma in children and young adults
https://braincanada.ca/funded-grants/detection-and-prevention-of-pypermutant-glioma-in-children-and-young-adultsNeed for project: Replication repair deficiency (RRD) is a genetic condition that significantly increases the risk of developing cancer, particularly early in life. Project Overview Need for project: Replication repair deficiency (RRD) is a genetic condition that significantly increases the risk of...
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Detection of misfolded TDP-43 in CSF of ALS cases: Diagnostic potential of confirmation-specific antibodies
https://braincanada.ca/funded-grants/detection-of-misfolded-tdp-43-in-csf-of-als-cases-diagnostic-potential-of-confirmation-specific-antibodiesA more streamlined way to diagnose ALS earlier is desperately needed as current methods can take up to two years and rely heavily on ruling out other conditions that share similar symptoms. Project Overview A more streamlined way to diagnose ALS earlier is desperately needed as current methods can...
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Detection of tandem repeat expansion in neurological disorders
https://braincanada.ca/funded-grants/detection-of-tandem-repeat-expansion-in-neurological-disordersIn the past decade, rapid development of software has allowed detection of a wide variety of genetic risk factors in brain disorders. Project Overview In the past decade, rapid development of software has allowed detection of a wide variety of genetic risk factors in brain disorders. It has...