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Managing chronic health conditions like chronic pain and Fetal Alcohol Spectrum Disorder (FASD) can be challenging, especially when support is limited. Our team has developed a mobile app called HELP (Health Education and Learning Platform) to support people in managing their health. Project...

On Sunday, September 28, Beyond the Pale Brewing Company in Ottawa proudly hosted its annual charity bike ride, bringing together more than 80 passionate participants in support of brain research. This year’s event carried profound personal meaning. Ottawa Charity Bike Ride Raises $2,500 for Brain...

The team wants to take a new breakthrough technology called Cyto-iGluSnFR (pronounced “sight-oh-eye-glue-sniffer”) and adapt it for the discovery of drugs to treat a variety of brain and eye diseases. Project Overview The team wants to take a new breakthrough technology called Cyto-iGluSnFR...

Recently, Dr. Honglin Luo, in collaboration with Dr. Neil Cashman, discovered that mutations in the ALS-linked SOD1 gene result in activation of a specific neuroinflammatory pathway called cGAS-STING. Project Overview Recently, Dr. Honglin Luo, in collaboration with Dr. Neil Cashman, discovered...

Gamma oscillations (GO) are electrical signals detected in the brain that are essential for memory and cognition. Project Overview Gamma oscillations (GO) are electrical signals detected in the brain that are essential for memory and cognition. GO are a product of the activity of a subpopulation of...

In childhood, medulloblastoma (a form of brain cancer) and neuroblastoma (a cancer that starts in the nerve cells) can be aggressive and hard to treat. Project Overview In childhood, medulloblastoma (a form of brain cancer) and neuroblastoma (a cancer that starts in the nerve cells) can be...

Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease in humans. Project Overview Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease in humans. The disease is caused by the degeneration of motor neurons that innervate the voluntary...

ALS is a disease that is characterized by degeneration of both upper and lower motor neurons, and while a significant proportion of work has focused on motor neurons in the spinal cord, the motor cortex in the brain, where electrical signals to your muscles originate have clear, but poorly Project...

Alzheimer’s disease (AD) affects nearly one million Canadians and remains without a cure. Although most research has focused on the build-up of abnormal proteins such as amyloid and tau, we now know that inflammation in the brain’s immune system plays a major role in how the disease starts and...

The brain cells in Alzheimer’s disease patients differ extensively from healthy brain cells at the molecular level: there are hundreds of genes that are normally active in the brain, but become inactive in Alzheimer’s. Project Overview The brain cells in Alzheimer’s disease patients differ...