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Medulloblastoma isthe most common brain cancer in children. Project Overview Medulloblastoma isthe most common brain cancer in children. The current treatment for it includestoxic chemotherapy drugs which leadsto severe long-term side effectslike cognitive impairment. Still, the treatment failsfor...

For decades, brain function was thought to follow a simple rule: each brain region performs a single function. It is now understood that the brain operates as a complex network, where different regions work together. The cortex (gray matter) forms the outer layer of the brain and is responsible for...

The brain is more than the sum of its parts. Project Overview The brain is more than the sum of its parts. Truly understanding the brain’s most intricate properties requires both a list of its individual parts, that is a census of the types of neurons it contains, and a map of how these parts are...

Isolated REM sleep behavior disorder (iRBD) is a sleep condition where people physically act out dreams because the normal muscle “paralysis” of REM sleep is lost. It is confirmed by an overnight sleep study with video monitoring. iRBD matters because it is one of the strongest known early warning...

The brain is an incredibly complex organ. Much of the brain’s complexity may be attributed to the circuitry that resides within. Project Overview The brain is an incredibly complex organ. Much of the brain’s complexity may be attributed to the circuitry that resides within. Synaptic connections are...

Maternal depression, particularly during pregnancy, has been well established as a risk factor for child socio-emotional problems. Project Overview Maternal depression, particularly during pregnancy, has been well established as a risk factor for child socio-emotional problems. However, the impact...

There are an increasing number of people living with dementia. Project Overview There are an increasing number of people living with dementia. Improving and maintaining quality of life is rated as the highest priority for people living with dementia and their caregivers. While many factors...

In Canada, 1 in 20 people live with depression. While many treatment options exist, a significant number of individuals do not respond adequately to current therapies, highlighting the urgent need for more effective solutions. One effective alternative to medication is theta burst stimulation (TBS)....

In developed countries, brain tumors are the leading cause of disability and death among children. Project Overview In developed countries, brain tumors are the leading cause of disability and death among children. Treatment advances have improved survival rates, but survival comes at a cost for...

Stroke is a major cause of death and disability. At present, there are no clear and effective therapies to aid the majority of patients who suffer stroke. Project Overview Stroke is a major cause of death and disability. At present, there are no clear and effective therapies to aid the majority of...