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Novel MRI biomarkers for monitoring disease progression in ALS
https://braincanada.ca/funded-grants/novel-mri-biomarkers-for-monitoring-disease-progression-in-alsFor this project Dr. Sanjay Kalra and his team aims to improve on current techniques to use magnetic resonance imaging (MRI) as a readily available way to examine if a potential new treatment is working to slow down progression of ALS. Project Overview For this project Dr. Sanjay Kalra and his team...
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Novel Repetitive Transcranial Magnetic Stimulation Paradigm to Reduce Cortical Hyperexcitability in Patients with ALS
https://braincanada.ca/funded-grants/novel-repetitive-transcranial-magnetic-stimulation-paradigm-to-reduce-cortical-hyperexcitability-in-patients-with-alsALS is a devastating neurological disease characterized by the progressive degeneration of motor neurons leading to paralysis and death. Project Overview ALS is a devastating neurological disease characterized by the progressive degeneration of motor neurons leading to paralysis and death....
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Novel Retinal Biomarkers for Alzheimer’s Disease
https://braincanada.ca/funded-grants/novel-retinal-biomarkers-for-alzheimer-s-diseaseIndividuals with Alzheimer’s suffer severe memory loss over time, and eventually are completely dependent on caregivers. Project Overview Individuals with Alzheimer’s suffer severe memory loss over time, and eventually are completely dependent on caregivers. Age is a significant risk factor, and...
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Novel therapeutic strategies to repair brain abnormalities in psychiatric disorders
https://braincanada.ca/funded-grants/novel-therapeutic-strategies-to-repair-brain-abnormalities-in-psychiatric-disordersCommunication between brain cells is essential for normal brain function. Project Overview Communication between brain cells is essential for normal brain function. Healthy brain cells are controlled through chemical messengers that stimulate or inhibit brain activity. Current theories indicate...
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Oncolytic rhabdovirus immunotherapy for brain cancer
https://braincanada.ca/funded-grants/oncolytic-rhabdovirus-immunotherapy-for-brain-cancerDr David Stojdl’s lab has custom‑built an oncolytic virus biotherapy specifically for the treatment of the devastating brain cancer, glioblastoma multiforme (GBM). Project Overview Dr David Stojdl’s lab has custom‑built an oncolytic virus biotherapy specifically for the treatment of the devastating...
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“One Brain” research for better brain health
https://braincanada.ca/about/news-updates/one-brain-research-for-better-brain-healthA Brain Canada-funded platform is enabling new technology for drug discovery, in order to address a wide range of brain diseases and disorders: from epilepsy to autism, and brain tumors to ALS. Bringing “One Brain” research to market for better brain health Dr. Kurrasch and colleague Dr. Deepika...
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Online detection and neuromodulation of replays during working memory in humans
https://braincanada.ca/funded-grants/online-detection-and-neuromodulation-of-replays-during-working-memory-in-humansWorking memory is our ability “keep in mind” information and manipulate it when it is not present in the environment. Project Overview Working memory is our ability “keep in mind” information and manipulate it when it is not present in the environment. It is central to many aspects of cognition,...
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Open Call for Future Leaders in Canadian Brain Research Program
https://braincanada.ca/about/news-updates/open-call-for-future-leaders-in-canadian-brain-research-programNew funding to support early-career investigators committed to improving brain health for all Brain Canada is pleased to announce the launch of the 2023 Future Leaders in Canadian Brain Research program. The Future Leaders in Canadian Brain Research Program provides essential seed funding to assist...
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Opening the World
https://braincanada.ca/about/news-updates/opening-the-worldWhen Dr. Monica Seger was 25, she received a grant to do a postdoctoral fellowship in the Netherlands. It was an experience that changed the trajectory of her life and research. As a young neuroendocrinologist, Monica benefited immensely from collaborating with scientists in a different culture. ...
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Opioid-Expressing B Cells Silence Tumor-Infiltrating Nociceptor Neurons
https://braincanada.ca/funded-grants/opioid-expressing-b-cells-silence-tumor-infiltrating-nociceptor-neuronsMelanoma, an aggressive skin cancer, often evades even today’s best immunotherapies. A surprising contributor is the nervous system. Tumors grow new nerve fibers and “talk” with nearby pain‑sensing neurons (nociceptors). Project Overview Melanoma, an aggressive skin cancer, often evades even...