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799 results found

Investigating altered functional brain networks in autism spectrum disorder

Autism Spectrum Disorder (ASD) is a complex developmental brain disorder characterised by impaired communication and repetitive behaviors, and is often accompanied by intellectual disability.


Grant type
Capacity building grants
Area of Research
Neurodevlopment
Competition
Future Leaders in Canadian Brain Research
Province
Alberta
Start Date
2020

Zebrafish as a novel animal model for the study of Zika virus neuropathogenesis in vivo

Infections with Zika virus (ZIKV) constitute a major global public health concern worldwide.


Grant type
Capacity building grants
Area of Research
Neurodevlopment
Competition
Future Leaders in Canadian Brain Research
Province
Québec
Start Date
2020

Direct microglial reprogramming to study Parkinson’s Disease

The human brain is a complex organ that presents many challenges for neuroscientists.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Future Leaders in Canadian Brain Research
Province
Québec
Start Date
2020

Dopaminergic modulation of stroke recovery

Strokes often cause brain damage that affects normal cognitive and sensorimotor functions.


Grant type
Capacity building grants
Area of Research
Injury
Competition
Future Leaders in Canadian Brain Research
Province
Québec
Start Date
2020

Disrupted SUMOylation facilitates rogue TDP-43 in ALS

Proteins are large molecules that play many essential roles in the body.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Trainee Program 2019
Province
Ontario
Start Date
2019

Biological and Pathological relevance of hnRNP A1B; An alternative splice variant of TDP-43

In 97 per cent of ALS cases and nearly half of cases of frontotemporal dementia, the TDP-43 protein is misplaced to an area outside the cell nucleus of the motor neuron called the cytoplasm.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Trainee Program 2019
Province
Québec
Start Date
2019

Validation of small molecules preventing TDP-43 aggregation as a therapeutic for Amyotrophic Lateral Sclerosis

TDP-43 is a protein that behaves abnormally in the motor neurons of 97 per cent of people with ALS.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Trainee Program 2019
Province
Ontario
Start Date
2019

2019 Turnbull-Tator Award in Spinal Cord Injury and Concussion Research


Grant type
Capacity building grants
Area of Research
Injury
Competition
Turnbull-Tator Award in Spinal Cord Injury and Concussion Research
Province
British Columbia
Start Date
2019

Exploitation of a new pharmacological target for the development and validation of new anti-inflammatory drugs

Neuroinflammation has been implicated in a diverse array of degenerative conditions, ranging from Multiple Sclerosis  to  Alzheimer’s  disease.


Grant type
Team grants
Area of Research
Neurodegeneration
Competition
CQDM - Brain Canada - SynergiQc
Province
Québec
Start Date
2019

Novel First-In-Class Melatonin MT2 Receptor Agonist for Neuropathic Pain: Investigational New Drug (IND) – Enabling Studies

Neuropathic pain is a chronic pain disorder resulting from damage to the nerves.


Grant type
Team grants
Area of Research
Central Nervous System
Competition
CQDM - Brain Canada - SynergiQc
Province
Québec
Start Date
2019