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887 results found

Molecular heterogeneity drives the clinical behaviour of childhood medulloblastoma

Brain cancer is the most common type of solid cancer in children in Canada, and medulloblastoma is the most common malignant brain cancer of childhood.


Grant type
Team grants
Area of Research
Cancer
Competition
Canadian Cancer Society Impact Grants
Province
Ontario
Start Date
2015

Novel Retinal Biomarkers for Alzheimer’s Disease

Individuals with Alzheimer’s suffer severe memory loss over time, and eventually are completely dependent on caregivers.


Grant type
Team grants
Area of Research
Neurodegeneration
Competition
BC Alzheimer's Research Award Program
Province
British Columbia
Start Date
2015

Targeting Amyloid Propagation in Alzheimer Disease: Structures, Immunology and Extracellular Vesicle Topology

A treatment or prevention of Alzheimer’s disease is a top priority for medical science.


Grant type
Team grants
Area of Research
Neurodegeneration
Competition
BC Alzheimer's Research Award Program
Province
British Columbia
Start Date
2015

Locally produced brain insulin in memory and Alzheimer’s disease: A multi-disciplinary approach to a key question

One percent of Alzheimer’s disease is the early-onset type that runs in families.


Grant type
Team grants
Area of Research
Neurodegeneration
Competition
BC Alzheimer's Research Award Program
Province
British Columbia
Start Date
2015

Distinct neuro-immune interactions drive sex differences in chronic pain

One of the most important advances in our understanding of chronic pain over the last decade or so is the realization that neurons are not the only cells in the central nervous system participating in the processing of pain signals.


Grant type
Team grants
Area of Research
Central Nervous System
Competition
2014 MIRI Team Grants
Province
Québec
Start Date
2015

Neurobiological correlates of TMS

Noninvasive brain stimulation is gaining acceptance as an alternate therapy for an increasing number of disorders, including major depression, schizophrenia, stroke and Parkinson’s disease.


Grant type
Team grants
Area of Research
Central Nervous System
Competition
2014 MIRI Team Grants
Province
Ontario
Start Date
2015

Canadian rTMS Treatment and Biomarker Network in Depression (CARTBIND) Trial

Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for patients with depression who have not responded to antidepressant medications.


Grant type
Team grants
Area of Research
Mental Health
Competition
2014 MIRI Team Grants
Province
Ontario
Start Date
2015

Stimulating Endogenous Regeneration of Photoreceptors as a Potential Cure for Blindness

Sight is the most precious sense, and patients suffering vision loss endure a devastating experience. Blindness often results from the gradual death of photoreceptors, the retinal cells that perceive light.


Grant type
Team grants
Area of Research
Central Nervous System
Competition
2014 MIRI Team Grants
Province
Ontario
Start Date
2015

Co-clinical trials in mice and humans in autism

Autism has many causes, yet no single cause explains why many children and adults have autism. This makes the symptoms of autism difficult, since how somebody responds to treatment might depend on what cause autism in the first place.


Grant type
Team grants
Area of Research
Neurodevelopment
Competition
Azrieli Neurodevelopment Research Program
Province
Ontario
Start Date
2014

Validation of ocular measures as potential biomarkers for early detection of brain amyloid and neurodegeneration

500,000 Canadians have dementia, a number that will double within a generation due to the ongoing aging demographics of the population, with annual costs estimated to increase from $15B currently to over $150B by the year 2050.


Grant type
Team grants
Area of Research
Neurodegeneration
Competition
The W. Garfield Weston Foundation
Province
Ontario
Start Date
2014