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Evaluating the role of intestinal inflammation in Alzheimer’s Disease
https://braincanada.ca/funded-grants/evaluating-the-role-of-intestinal-inflammation-in-alzheimer-s-diseaseRecent findings suggest that the gut and brain are closely connected, and this link may be important in Alzheimer’s disease (AD). Project Overview Recent findings suggest that the gut and brain are closely connected, and this link may be important in Alzheimer’s disease (AD). Helpful products made...
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Evaluating therapeutic stimulation in a mouse model of perinatal stroke
https://braincanada.ca/funded-grants/evaluating-therapeutic-stimulation-in-a-mouse-model-of-perinatal-strokeNeonatal strokes occur in approximately 1 in 1500 term births and is the leading cause of hemiplegic cerebral palsy (HCP). Project Overview Neonatal strokes occur in approximately 1 in 1500 term births and is the leading cause of hemiplegic cerebral palsy (HCP). The ischemic event leaves most...
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Evaluation of electrical activity as a tumour suppressor in medulloblastoma
https://braincanada.ca/funded-grants/evaluation-of-electrical-activity-as-a-tumour-suppressor-in-medulloblastomaDr. Garzia works on a type of pediatric brain cancer called medulloblastoma. Project Overview Dr. Garzia works on a type of pediatric brain cancer called medulloblastoma. Kids affected by this tumor are either not cured or experience severe side effects due to the aggressive therapy. This proposal...
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Evaluation of Long-Axis Hippocampal Subfield Volumetry as a neuroimaging biomarker for Alzheimer’s disease
https://braincanada.ca/funded-grants/evaluation-of-long-axis-hippocampal-subfield-volumetry-as-a-neuroimaging-biomarker-for-alzheimer-s-diseaseThe hippocampus is the brain region which shows the most severe changes in patients with Alzheimer’s disease. Project Overview The hippocampus is the brain region which shows the most severe changes in patients with Alzheimer’s disease. Magnetic resonance imaging can be used to measure these...
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Evaluation of the Contribution to Brain Canada Foundation’s Canada Brain Research Fund 2011-12 to 2015-16
https://braincanada.ca/about/news-updates/evaluation-of-the-contribution-to-brain-canada-foundation-s-canada-brain-research-fund-2011-12-to-2015-16The evaluation of Heath Canada’s contribution to Brain Canada Foundation’s Canada Brain Research Fund (CBRF) was undertaken in fulfillment of the requirements of the Financial Administration Act. The purpose of the evaluation was to assess the relevance and performance of the contribution to the...
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Evaluation of the Kids Write Network (KWN) intervention with children of severely ill parents: a qualitative and quantitative pilot study
https://braincanada.ca/funded-grants/evaluation-of-the-kids-write-network-kwn-intervention-with-children-of-severely-ill-parents-a-qualitative-and-quantitative-pilot-studyAdolescence represents a unique developmental window of the life cycle to adopt healthy behaviours that will support psychosocial adjustment and well-being during adolescence and adulthood (World Health Organization, 2001). Project Overview Adolescence represents a unique developmental window of...
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Evaluation of the pathogenic role of autoantibodies on ependymal cells in multiple sclerosis
https://braincanada.ca/funded-grants/evaluation-of-the-pathogenic-role-of-autoantibodies-on-ependymal-cells-in-multiple-sclerosisMultiple sclerosis (MS) is a chronic disease that affects the brain, leading to difficulties with movement, thinking, and mood. While current treatments help reduce relapses, they often fail to prevent the steady worsening of disability that many people with MS experience over time. Project...
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Evaluation of the role of EMMPRIN and MMP-9 in extracellular matrix degradation during ALS
https://braincanada.ca/funded-grants/evaluation-of-the-role-of-emmprin-and-mmp-9-in-extracellular-matrix-degradation-during-alsAmyotrophic Lateral Sclerosis (ALS) is a fatal disease that progressively destroys motor neurons, leading to paralysis and death, with no current cure. Project Overview Amyotrophic Lateral Sclerosis (ALS) is a fatal disease that progressively destroys motor neurons, leading to paralysis and death,...
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Examining the neurobiological substrates of antidepressant effects of psilocybin: a PET imaging study using SYNVEST1
https://braincanada.ca/funded-grants/examining-the-neurobiological-substrates-of-antidepressant-effects-of-psilocybin-a-pet-imaging-study-using-synvest1In Canada, over 1 million people have been diagnosed with bipolar disorder (BD) in their lifetime. Project Overview In Canada, over 1 million people have been diagnosed with bipolar disorder (BD) in their lifetime. BD is characterized by recurrent episodes of depression and (hypo)mania. Many people...
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Examining the role of KCC2 in maintaining the balance between excitation and inhibition in ALS
https://braincanada.ca/funded-grants/examining-the-role-of-kcc2-in-maintaining-the-balance-between-excitation-and-inhibition-in-alsEach muscle in the body receives electrical signals through motor neurons that will stimulate it to contract. Project Overview Each muscle in the body receives electrical signals through motor neurons that will stimulate it to contract. Other specialized neurons inhibit these signals, allowing...