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PHOTO: Brain Canada President & CEO Viviane Poupon and Canadian Neuromuscular Disease Registry Executive Director Victoria Hodgkinson in Calgary, Alberta on May 27, 2025. Brain Canada is investing in transformative research platforms across the country to accelerate neuroscience discovery and...

Neuroinflammation has been implicated in a diverse array of degenerative conditions, ranging from Multiple Sclerosis  to  Alzheimer’s  disease. Project Overview Neuroinflammation has been implicated in a diverse array of degenerative conditions, ranging from Multiple Sclerosis  to  Alzheimer’s ...

Dr. Maria Vera Ugalde loves fundamental biology. As a biochemist at McGill University, she spends her days using advanced microscopy techniques to see into the intricate workings of our cells. Will this new way of looking at certain protective proteins better explain their role in ALS? Award:...

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating neurodegenerative diseases which have overlap in pathological features and the genetic basis. Project Overview Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating...

Medulloblastoma (MB) is a brain cancer that affects children. Medulloblastoma (MB) is a brain cancer that affects children. Current treatment for MB leaves patients with debilitating brain issues. We found that aggressive MB have low activity of a process called nonsense mediated decay (NMD)....

Women have a higher lifetime risk of Alzheimer’s disease (AD), possibly due to female-specific factors like menopause and pregnancy history. Project Overview Women have a higher lifetime risk of Alzheimer’s disease (AD), possibly due to female-specific factors like menopause and pregnancy history....

TDP-43 is an essential DNA/RNA binding protein at the epicenter of Amyotrophic Lateral Sclerosis (ALS). Project Overview TDP-43 is an essential DNA/RNA binding protein at the epicenter of Amyotrophic Lateral Sclerosis (ALS). Nearly all cases of ALS present with TDP-43 pathology involving nuclear to...

We are working on an innovative project to improve speech therapy for children who have trouble speaking or understanding language. Project Overview We are working on an innovative project to improve speech therapy for children who have trouble speaking or understanding language. We’re using a type...

Depression is a common mental health condition that affects millions of Canadians. Project Overview Depression is a common mental health condition that affects millions of Canadians. While there are treatment options available, some patients do not respond to conventional antidepressants and...