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Enhancing walking recovery after stroke through a 24-hour behaviour change approach
https://braincanada.ca/funded-grants/enhancing-walking-recovery-after-stroke-through-a-24-hour-behaviour-change-approachWe are looking at how a behaviour change program can help stroke survivors recover their ability to walk better. Project Overview We are looking at how a behaviour change program can help stroke survivors recover their ability to walk better. We are aiming to recruit 24 people who have had a stroke...
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Ensuring equitable access to inpatient rehabilitation for people living with dementia: An effectiveness-implementation randomized trial
https://braincanada.ca/funded-grants/ensuring-equitable-access-to-inpatient-rehabilitation-for-people-living-with-dementia-an-effectiveness-implementation-randomized-trialOne in five older adults with dementia is hospitalized each year. Project Overview One in five older adults with dementia is hospitalized each year. One in three hospitalized older adults will lose independence in transferring, eating, ambulating, dressing, or bathing, which increases nursing home...
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Ensuring Sex & Gender Representation in Dementia Research
https://braincanada.ca/about/news-updates/ensuring-sex-gender-representation-in-dementia-researchWilfred and Joyce Posluns Chair The Women, Sex, Gender, and Dementia (WSGD) cross-cutting program, led by Dr. Gillian Einstein, Wilfred and Joyce Posluns Chair in Women’s Brain Health and Aging at the University of Toronto, has its eye across the entire Canadian Consortium on Neurodegeneration in...
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Epigenetic mechanisms underlying dendritic atrophy in ALS
https://braincanada.ca/funded-grants/epigenetic-mechanisms-underlying-dendritic-atrophy-in-alsMotor neurons are made up of three distinct regions. The top of the neuron is composed of branches like a tree called dendrites that receive information to transmit. Project Overview Motor neurons are made up of three distinct regions. The top of the neuron is composed of branches like a tree...
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Epigenetics and mental health: the Canadian neuroepigenetics network
https://braincanada.ca/funded-grants/epigenetics-and-mental-health-the-canadian-neuroepigenetics-networkPsychiatry, like all areas of medicine and biology, has long considered the origins of individual differences. Project Overview Psychiatry, like all areas of medicine and biology, has long considered the origins of individual differences. This issue ultimately produced a nature vs nurture schism...
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Epitranscriptomic regulation of sleep, neurodegeneration, and longevity
https://braincanada.ca/funded-grants/epitranscriptomic-regulation-of-sleep-neurodegeneration-and-longevityThis research proposal investigates how a chemical modification called N6-methyladenosine (m6A) on messenger RNA influences brain health, specifically focusing on its role in sleep regulation, learning and memory, and neurodegenerative diseases such as Alzheimer’s. This research proposal...
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Establishing protein signatures of MRI-detected vascular brain injury in circulating endothelial-derived extracellularvesicles in Alzheimer’s disease
https://braincanada.ca/funded-grants/establishing-protein-signatures-of-mri-detected-vascular-brain-injury-in-circulating-endothelial-derived-extracellularvesicles-in-alzheimer-s-diseaseAge-related dementias are reaching epidemic levels, affecting over 600,000 Canadians. Project Overview Age-related dementias are reaching epidemic levels, affecting over 600,000 Canadians. The most common cause of age-related dementia is Alzheimer’s disease (AD). The defining pathology of AD is the...
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EthoLab: A platform for neurophysiological studies of natural behavior
https://braincanada.ca/funded-grants/etholab-a-platform-for-neurophysiological-studies-of-natural-behaviorSystems neuroscience owes much of its success to an empirical tradition of using simplified laboratory settings that carefully control sensory stimuli, motor responses, or other task-relevant variables in order to identify the neural mechanisms underlying different behavioral functions. Project...
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Evaluating an AI-Driven Mental Health App (LifeLine) in Northern Communities: A Randomized Controlled Trial
https://braincanada.ca/funded-grants/evaluating-an-ai-driven-mental-health-app-lifeline-in-northern-communities-a-randomized-controlled-trialMany people in northern and Indigenous communities in Saskatchewan face challenges in accessing mental health support due to distance, limited services, and long wait times. Project Overview Many people in northern and Indigenous communities in Saskatchewan face challenges in accessing mental...
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Evaluating an innovative e-mental health solution to support youth with mental health disorders in Northwestern Ontario
https://braincanada.ca/funded-grants/evaluating-an-innovative-e-mental-health-solution-to-support-youth-with-mental-health-disorders-in-northwestern-ontarioMany youth suffer from mental health-related brain disorders which can have devastating consequences Effective treatment is desperately needed. Project Overview Many youth suffer from mental health-related brain disorders which can have devastating consequences Effective treatment is desperately...