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Evaluating community-based exercise and rehabilitation for physical and personal achievement among people living with chronic neurological conditions
https://braincanada.ca/funded-grants/evaluating-community-based-exercise-and-rehabilitation-for-physical-and-personal-achievement-among-people-living-with-chronic-neurological-conditionsExercise and rehabilitation can help people with neurological conditions to improve physical function even years after a diagnosis. Yet, after hospital discharge, there are few available services for people with neurological conditions. Project Overview Exercise and rehabilitation can help people...
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Evaluating DLK activity in brain samples from Huntington’s disease patients
https://braincanada.ca/funded-grants/evaluating-dlk-activity-in-brain-samples-from-huntington-s-disease-patients"Background:Within the realm of neurodegenerative diseases, there is still a lack of effective disease-modifying treatments. Huntington’s Disease (HD) is no less immune to this issue, with only symptomatic treatment options being available for patients." Project Overview “Background:Within the...
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Evaluating the histone variant macroH2A1.1 as a master regulator of PARP1-Sirt1 balance in Alzheimer’s disease
https://braincanada.ca/funded-grants/evaluating-the-histone-variant-macroh2a1-1-as-a-master-regulator-of-parp1-sirt1-balance-in-alzheimer-s-diseaseAlzheimer’s Disease (AD) is characterized by memory decline and neuronal pathology, including amyloid β (Aβ)plaques and oxidative stress. Project Overview Alzheimer’s Disease (AD) is characterized by memory decline and neuronal pathology, including amyloid β (Aβ)plaques and oxidative stress. These...
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Evaluating the role of intestinal inflammation in Alzheimer’s Disease
https://braincanada.ca/funded-grants/evaluating-the-role-of-intestinal-inflammation-in-alzheimer-s-diseaseRecent findings suggest that the gut and brain are closely connected, and this link may be important in Alzheimer’s disease (AD). Project Overview Recent findings suggest that the gut and brain are closely connected, and this link may be important in Alzheimer’s disease (AD). Helpful products made...
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Evaluating therapeutic stimulation in a mouse model of perinatal stroke
https://braincanada.ca/funded-grants/evaluating-therapeutic-stimulation-in-a-mouse-model-of-perinatal-strokeNeonatal strokes occur in approximately 1 in 1500 term births and is the leading cause of hemiplegic cerebral palsy (HCP). Project Overview Neonatal strokes occur in approximately 1 in 1500 term births and is the leading cause of hemiplegic cerebral palsy (HCP). The ischemic event leaves most...
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Evaluation of electrical activity as a tumour suppressor in medulloblastoma
https://braincanada.ca/funded-grants/evaluation-of-electrical-activity-as-a-tumour-suppressor-in-medulloblastomaDr. Garzia works on a type of pediatric brain cancer called medulloblastoma. Project Overview Dr. Garzia works on a type of pediatric brain cancer called medulloblastoma. Kids affected by this tumor are either not cured or experience severe side effects due to the aggressive therapy. This proposal...
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Evaluation of Long-Axis Hippocampal Subfield Volumetry as a neuroimaging biomarker for Alzheimer’s disease
https://braincanada.ca/funded-grants/evaluation-of-long-axis-hippocampal-subfield-volumetry-as-a-neuroimaging-biomarker-for-alzheimer-s-diseaseThe hippocampus is the brain region which shows the most severe changes in patients with Alzheimer’s disease. Project Overview The hippocampus is the brain region which shows the most severe changes in patients with Alzheimer’s disease. Magnetic resonance imaging can be used to measure these...
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Evaluation of the Contribution to Brain Canada Foundation’s Canada Brain Research Fund 2011-12 to 2015-16
https://braincanada.ca/about/news-updates/evaluation-of-the-contribution-to-brain-canada-foundation-s-canada-brain-research-fund-2011-12-to-2015-16The evaluation of Heath Canada’s contribution to Brain Canada Foundation’s Canada Brain Research Fund (CBRF) was undertaken in fulfillment of the requirements of the Financial Administration Act. The purpose of the evaluation was to assess the relevance and performance of the contribution to the...
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Evaluation of the Kids Write Network (KWN) intervention with children of severely ill parents: a qualitative and quantitative pilot study
https://braincanada.ca/funded-grants/evaluation-of-the-kids-write-network-kwn-intervention-with-children-of-severely-ill-parents-a-qualitative-and-quantitative-pilot-studyAdolescence represents a unique developmental window of the life cycle to adopt healthy behaviours that will support psychosocial adjustment and well-being during adolescence and adulthood (World Health Organization, 2001). Project Overview Adolescence represents a unique developmental window of...
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Evaluation of the pathogenic role of autoantibodies on ependymal cells in multiple sclerosis
https://braincanada.ca/funded-grants/evaluation-of-the-pathogenic-role-of-autoantibodies-on-ependymal-cells-in-multiple-sclerosisMultiple sclerosis (MS) is a chronic disease that affects the brain, leading to difficulties with movement, thinking, and mood. While current treatments help reduce relapses, they often fail to prevent the steady worsening of disability that many people with MS experience over time. Project...