Répertoire des subventions financées

From Space to Memory Under Pathological Tau

Aperçu du projet

Among the earliest signs of preclinical Alzheimer’s disease (AD) are navigation impairments and the presence of abnormal Tau (aTau) proteins in the entorhinal cortex (EC), a brain region that represents space and movement. As AD progresses aTau spreads to the subiculum (Sub), a key region for memory encoding and retrieval.…

Canadian Consortium on Neurodegeneration In Aging (CCNA) – Phase 2

Brain and cognitive effects of long-term gender affirming hormone therapy in aging trans women

Aperçu du projet

Trans women may take estradiol-based gender affirming hormone therapy (GAHT) into their old age. Yet, we know little about the long-term brain health effects of GAHT. We propose to further our understanding of the earliest causes and signs of cognitive and brain aging effects in women by exploring the effects…

Sex differences in the innate immune response associated with Parkinson’s Disease

Aperçu du projet

Age is the most important risk factor for Parkinson’s Disease (PD), followed by sex, with a higher risk in males. Studies show that brain inflammation occurs early in the disease and persists throughout its course. As such, inflammation is likely to contribute to the disease. In the brain, the main…

Using a virtual care platform to deliver peer-led mental health support to rural and remote communities in BC: A randomized wait-list controlled trial of the REACHOUT intervention

Aperçu du projet

Dr. Tang and her team at the University of British Columbia will use a virtual care platform to deliver peer-led mental health support to rural and remote communities in BC, through an intervention called REACHOUT, created with support from a previous JDRF grant. Given the shortage of mental health professionals…