Répertoire des subventions financées

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Functional investigation of a novel genetic player in brain development

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Central Nervous System

  • Disease Area

    Other

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Date de Début

    2025

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

The human brain’s development relies on precisely coordinated genetic programs that ensure proper wiring and function. When these processes go awry, neurodevelopmental disorders, including severe epileptic encephalopathies, can arise. Lennox-Gastaut Syndrome (LGS) is a rare and severe childhood epilepsy that is often resistant to current treatments, suggesting the involvement of…

Discovering “hidden” causal mutations in autism using long-read RNAseq and proteomics in neuron development

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Neurodevelopment

  • Disease Area

    Autism

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Date de Début

    2025

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

Autism spectrum disorder (ASD) is a complex condition affecting communication, social interactions, and behavior in approximately 1–2% of people worldwide. While some cases of ASD can be linked to specific genetic changes, most remain unexplained, leaving families and clinicians without clear answers. Recent studies suggest that our current understanding of…

Examining the neurobiological substrates of antidepressant effects of psilocybin: a PET imaging study using SYNVEST1

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Mental Health

  • Disease Area

    Mental illness

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Date de Début

    2025

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

In Canada, over 1 million people have been diagnosed with bipolar disorder (BD) in their lifetime. BD is characterized by recurrent episodes of depression and (hypo)mania. Many people do not improve when they receive a recommended treatment, leading to treatment resistance. Psilocybin has been identified as a potential option to…

Utilizing next generation intersectional approaches to define the roles of POMC neuron subpopulations

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Central Nervous System

  • Disease Area

    Other

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Date de Début

    2025

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

The central nervous system controls numerous processes, including appetite and body weight regulation. Given the alarming rise in global obesity, understanding how the CNS controls appetite is crucial. Among the cell types involved, neurons expressing the gene "Pro-opiomelanocortin" (POMC) are particularly important. Loss of POMC neurons or the POMC gene…

First-Principle modeling of Diffusion MRI in Brain tumor

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Cancer

  • Disease Area

    Brain Cancer

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Date de Début

    2025

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

Glioblastoma is the most common primary malignant brain tumor in the adult population with a very poor prognostic. The combination of surgery, chemotherapy and radiotherapy are used as treatment. Magnetic Resonance Imaging (MRI) is used to delineate the disease before surgery and to monitor patients after surgery. Two of the…