693 ésultat(s) trouvé(s)
Laminar regulation of hemodynamics in primary auditory cortex
Aperçu du projet
Brain disorders and disease represent an immense societal burden and the leading cost to the Canadian health care system. Although research in animal models has led to major advances in our understanding of brain function and dysfunction at the cellular level, a major challenge remains bridging these findings from animals…
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Voir le projet et les chercheursA Human System to study Immune-Ependymal Cell Relationships
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Ependymal cells are a largely understudied barrier cell type in the brain that provide a wall between brain tissue and brain fluid (cerebral spinal fluid, CSF), playing an important role in regulating fluid balance. These cells become dysfunctional in many brain diseases and this dysfunction contributes to neurodegeneration that occurs…
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Voir le projet et les chercheursDetection of tandem repeat expansion in neurological disorders
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In the past decade, rapid development of software has allowed detection of a wide variety of genetic risk factors in brain disorders. It has improved clinical diagnosis and gene discovery for numerous human brain disorders. However, the casual genetic risk factors identified so far generally confer less risk than expected…
Projet en cours
Voir le projet et les chercheursNeural predictors of theta burst stimulation
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In Canada, 1 in 20 people live with depression. Substantial efforts have been made over the years to develop new treatments to enhance therapeutic options. One effective alternative to medication is theta burst stimulation (TBS). This technique uses magnetic fields applied to the outside of the head to modulate brain…
Projet en cours
Voir le projet et les chercheursMulti-scale analyses of brain connectivity and dynamics in autism spectrum conditions
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Autism spectrum disorder (ASD) affects approximately 1 in 70 children and is associated to a considerable burden for affected individuals, their families, and health care at large. As ASD remains not very well understood from a neuroscientific perspective, we currently lack diagnostic and intervention approaches that target potential biological mechanisms.…