727 ésultat(s) trouvé(s)
The Applied Organoid Core (ApOC): a organoid production platform for modelling human brain development and disease
Aperçu du projet
Current preclinical models to address neurological disorders fail to accurately portray human physiology. First, traditional tissue culture in which neuronal cells are grown in monolayer do not recapitulate the complex heterogeneity and function of the human brain. Second, animal models such as rodents lack many specific biological features unique to…
Projet en cours
Voir le projet et les chercheursThe McConnell Brain Imaging Center: A world-renowned multidisciplinary platform dedicated to brain research using multimodal neuroimaging and neuroinformatics
Aperçu du projet
Thanks to the late Dr. William Feindel’s vision, who in the 1970’s believed that brain imaging was the “future for neurology and neurosurgery”, and to a generous donation, the Montreal Neurological Institute (The Neuro) inaugurated the McConnell Brain Imaging Center (BIC) in 1984. This pioneering landmark was preceded (and followed)…
Projet en cours
Voir le projet et les chercheursCFMM: Canada’s National Ultra-High Field MRI Platform
Aperçu du projet
Brain imaging using magnetic resonance imaging (MRI) is an essential tool in modern neuroscience, with many uses for examining brain structure and function in health and disease. The Centre for Functional and Metabolic Mapping (CFMM) at Western’s Robarts Research Institute houses Canada’s only collection of high-field (3 Tesla human) and…
Projet en cours
Voir le projet et les chercheursScreening of glioblastoma oncometabolite by ultrafast solid phase microextraction approach
Aperçu du projet
Need for project: The rate of success of a given treatment for brain cancer is dependent on early diagnosis followed by qualification for surgery, which to date remains as the course of treatment with the highest survival rate for brain cancer patients. In this regard, a fast and reliable population…
Projet terminé
Voir le projet et les chercheursDetection and prevention of pypermutant glioma in children and young adults
Aperçu du projet
Need for project: Replication repair deficiency (RRD) is a genetic condition that significantly increases the risk of developing cancer, particularly early in life. Gliomas are the most common brain tumour seen in children and young adults (CAYA), and occur frequently in RRD. Currently, the prevalence of RRD has not been…