Répertoire des subventions financées

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Determining the contribution of acute viral infection on the onset and progression of ALS

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    ALS

  • Compétition

    2023 ALS Canada - Brain Canada Trainee Program

  • Province

    Ontario

  • Date de Début

    2023

  • Montant total du financement

    $25,000

Aperçu du projet

Almost all amyotrophic lateral sclerosis (ALS) is accompanied by neuronal cytoplasmic aggregates of TAR DNA-binding protein-43 (TDP-43). TDP-43 is an RNA-binding protein that regulates RNA expression and function, including mRNA translation. The mechanisms by which TDP-43 pathology contributes to ALS remain incompletely understood, hampering the development of a rational therapy…

Projet en cours

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Defective protein translation: a causative pathway in ALS?

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    ALS

  • Compétition

    2023 ALS Canada - Brain Canada Trainee Program

  • Province

    British Columbia

  • Date de Début

    2023

  • Montant total du financement

    $75,000

Aperçu du projet

Almost all amyotrophic lateral sclerosis (ALS) is accompanied by neuronal cytoplasmic aggregates of TAR DNA-binding protein-43 (TDP-43). TDP-43 is an RNA-binding protein that regulates RNA expression and function, including mRNA translation. The mechanisms by which TDP-43 pathology contributes to ALS remain incompletely understood, hampering the development of a rational therapy…

Projet en cours

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Development of a shared decision-making aid for bulbar symptom management in ALS

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    ALS

  • Compétition

    2023 ALS Canada - Brain Canada Trainee Program

  • Province

    Ontario

  • Date de Début

    2023

  • Montant total du financement

    $50,000

Aperçu du projet

Bulbar disease, which affects speech and swallowing functions, is considered to be one of the most debilitating aspects of ALS by patients. It is characterized by a rapid progression, short survival after diagnosis, and poorer quality of life. Clinical management of bulbar symptoms is focused on optimizing patients’ function and…

Projet en cours

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Resetting Microglia Activation in Offspring Exposed to Maternal High-Fat Diet

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Central Nervous System

  • Disease Area

    Other

  • Compétition

    Master's Personnel Awards for Black Scholars

  • Province

    Ontario

  • Date de Début

    2023

  • Montant total du financement

    $50,000

Aperçu du projet

Nutrition and diet are factors in life that contribute drastically to a person’s brain health, and overall quality of life, and high-fat diets can be considered a cause of many harmful physical and cognitive conditions. In rodent models, exposing the mother to a high-fat diet has been shown to negatively…

Projet en cours

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Sex-related differences in visuomotor skills, cognition, and emotionality following concussive injury

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Accident vasculaire cérébral et lésion cérébrale

  • Disease Area

    Brain Injury

  • Compétition

    Master's Personnel Awards for Black Scholars

  • Province

    Ontario

  • Date de Début

    2023

  • Montant total du financement

    $10,000

Aperçu du projet

The proposed research project aims to study the differences in brain function behaviour between male and female university athletes who have experienced a concussion. The research will examine hand-eye coordination, thinking and mental processing, and feelings and emotions of these athletes. The research will also investigate the impact of concussion…

Projet en cours

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