Répertoire des subventions financées

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GPNMB CAR-T Cells as a Multi-Pronged Immunotherapeutic Approach for Glioblastoma

  • Type de subvention

    Team grants

  • Domaine de recherche

    Cancer

  • Disease Area

    Brain Cancer

  • Compétition

    2025 Translational Research Grants in Brain Cancer

  • Province

    Ontario

  • Date de Début

    2025

  • Montant total du financement

    $1,000,000

  • Contribution Santé Canada

    $500,000

Aperçu du projet

Glioblastoma (GBM) is the most common and deadly adult brain cancer. GBM is particularly challenging because it contains many different cell types that help it grow and resist treatment, one of which are immune cells called macrophages. We identified a protein, GPNMB, found on the surface of both cancer cells…

Projet en cours

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Engaging neural stem cells for enhanced brain regeneration

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Neurodevelopment

  • Disease Area

    Other

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Alberta

  • Date de Début

    2025

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

Neurological disorders affect more than 1 in 3 people, making them a leading cause of illness and disability worldwide. Currently, there are no effective regenerative therapies, capable of halting progression or reversing neurological diseases. The presence of resident neural stem cells in the adult human central nervous system (brain and…

Projet en cours

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Unravelling the NeuroMetabolic Circuits of Anti-Obesity medications

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Central Nervous System

  • Disease Area

    Other

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Date de Début

    2025

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

Decades of research suggest that obesity is a brain disease. The brain regulates appetite, and when key pathways are disrupted, it can lead to excessive weight gain. This contributes to the classification of obesity as a chronic, relapsing disease rather than simply a result of lifestyle choices. Obesity affects millions…

Projet en cours

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The Effect of Vagus Nerve Stimulation on the Autonomic Network in Patients with Drug-Resistant Epilepsy

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Central Nervous System

  • Disease Area

    Epilepsy

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Date de Début

    2025

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

Epilepsy is a common brain disorder that causes repeated seizures and can significantly affect a person’s daily life. One-third of people with epilepsy have drug-resistant epilepsy (DRE), meaning their seizures do not respond to medications to control seizures. For those who cannot have surgery, treatments like Vagus Nerve Stimulation (VNS)…

Projet en cours

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Functional investigation of a novel genetic player in brain development

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Central Nervous System

  • Disease Area

    Other

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Date de Début

    2025

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

The human brain’s development relies on precisely coordinated genetic programs that ensure proper wiring and function. When these processes go awry, neurodevelopmental disorders, including severe epileptic encephalopathies, can arise. Lennox-Gastaut Syndrome (LGS) is a rare and severe childhood epilepsy that is often resistant to current treatments, suggesting the involvement of…

Projet en cours

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