Répertoire des subventions financées

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Rising Star Award in Mental Health Research, in memory of Vivian Distler

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Mental Health

  • Disease Area

    Mental illness

  • Compétition

    Rising Stars Trainee Awards

  • Province

    Alberta

  • Date de Début

    2026

  • Montant total du financement

    $12,000

Aperçu du projet

The Role of the Hypocretin-Dorsal Raphe Nucleus Circuit in Chronic Social Isolation and Acute Social Stress Social behaviour is especially sensitive to stress, and isolation during youth can have long-lasting effects on how the brain supports healthy social interactions. This project will study how chronic social isolation in adolescence alters…

Projet en cours

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Investigating the Templated Propagation of the ALS-related Protein FUS in iPSC-derived Cerebral Organoids

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    ALS

  • Compétition

    Rising Stars Trainee Awards

  • Province

    Québec

  • Date de Début

    2026

  • Montant total du financement

    $12,000

Aperçu du projet

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that causes muscle weakness and paralysis, partly due to the buildup of protein aggregates in nerve cells. One key protein, FUS, normally helps process RNA and produce proteins, but mutations can cause it to form harmful aggregates. This project will use “mini…

Projet en cours

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Identification of novel ALS targets and development of non-invasive nanodiscs for ASO delivery

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    ALS

  • Compétition

    Rising Stars Trainee Awards

  • Province

    Ontario

  • Date de Début

    2026

  • Montant total du financement

    $12,000

Aperçu du projet

Amyotrophic Lateral Sclerosis (ALS) can result from many different mutations in the same gene, making mutation-specific treatments challenging. This project focuses on using antisense oligonucleotides (ASOs) to selectively target mutant RNA from the VCP gene, reducing production of the harmful protein while preserving the normal version. To overcome the major…

Projet en cours

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Characterization of Glutamatergic Premotor Spinal V3 Interneurons in a SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    ALS

  • Compétition

    Rising Stars Trainee Awards

  • Province

    Nova Scotia

  • Date de Début

    2026

  • Montant total du financement

    $12,000

Aperçu du projet

Amyotrophic Lateral Sclerosis (ALS) is a progressive disease that destroys the motor neurons needed for movement, speech, and breathing, but new research shows that other spinal cord cells called interneurons may be affected even earlier. This project focuses on V3 interneurons, which help coordinate movement and appear to die off…

Projet en cours

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Evaluation of the role of EMMPRIN and MMP-9 in extracellular matrix degradation during ALS

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    ALS

  • Compétition

    Rising Stars Trainee Awards

  • Province

    Québec

  • Date de Début

    2026

  • Montant total du financement

    $12,000

Aperçu du projet

Amyotrophic Lateral Sclerosis (ALS) is a fatal disease that progressively destroys motor neurons, leading to paralysis and death, with no current cure. This project investigates how the protein EMMPRIN and the enzyme MMP-9 may contribute to ALS by degrading the extracellular matrix, which supports motor neurons. Using an ALS mouse…

Projet en cours

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