Répertoire des subventions financées

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Can a virtual AI platform make speech-language care more accessible for ALS?

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    ALS

  • Compétition

    2025 ALS Canada - Brain Canada Trainee Program

  • Province

    Ontario

  • Date de Début

    2026

  • Montant total du financement

    $165,000

Aperçu du projet

Feasibility RCT of a digital tool for management of bulbar disease in ALS Losing the ability to speak and swallow/eat are among the most devastating consequences of amyotrophic lateral sclerosis (ALS). Speech language pathology (SLP) clinicians are key specialists who support patients with bulbar ALS, providing means of tracking/monitoring the…

Projet en cours

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How does cellular stress impact TDP-43, a key ALS protein?

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    ALS

  • Compétition

    2025 ALS Canada - Brain Canada Trainee Program

  • Province

    Ontario

  • Date de Début

    2025

  • Montant total du financement

    $75,000

Aperçu du projet

Regardless of disease etiology, ~97% of ALS patients display TDP-43 pathology. TDP-43 is an RNA-binding protein that is involved in the cellular stress response. Following a stressor, TDP-43 translocates to the cytosol and is thought to be protective. However, with chronic stress and/or ALS-relevant mutations TDP-43 is depleted from the…

Projet en cours

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Can targeting support cells improve muscle-nerve repair in ALS?

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    ALS

  • Compétition

    2025 ALS Canada - Brain Canada Trainee Program

  • Province

    Québec

  • Date de Début

    2025

  • Montant total du financement

    $75,000

Aperçu du projet

Study of perisynaptic Schwann cells contribution on NMJ reinnervation efficiency in ALS Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by motoneurons loss and leading to death within 5 years after diagnosis. Changes in the neuromuscular junctions (NMJs) constitute one of the hallmarks of ALS pathophysiology occurring prior to…

Projet en cours

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Can a novel animal model of ALS help us understand if the spread of misfolded proteins contributes to disease progression?

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    ALS

  • Compétition

    ALS Canada - Brain Canada Clinical Research Fellowship 2025

  • Province

    Alberta

  • Date de Début

    2025

  • Montant total du financement

    $200,000

  • Contribution Santé Canada

    $100,000

Aperçu du projet

TDP-43, SOD1, and FUS proteinopathies in vivo: interrogating prion-like mechanisms and drug rescue in zebrafish and ALS hiPSC-derived neuron xenotransplant models RATIONALE: Proteins of ALS-associated gene variants in TDP-43, SOD1, and FUS exhibit misfolding and prion-like properties under certain conditions. Whether these prion-like properties occur in a complex central nervous…

Projet en cours

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Rising Star Award in Mental Health Research, in memory of Vivian Distler

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Mental Health

  • Disease Area

    Mental illness

  • Compétition

    Rising Stars Trainee Awards

  • Province

    Ontario

  • Date de Début

    2026

  • Montant total du financement

    $12,000

Aperçu du projet

Personalized Modeling and Optimization of Transcranial Temporal Interference Stimulation in Major Depressive Disorder Depression affects nearly 2 million Canadians, and about one-third of patients do not find relief from current treatments, highlighting the need for new approaches. This project investigates a non-invasive brain stimulation method called transcranial Temporal Interference Stimulation…

Projet en cours

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