693 ésultat(s) trouvé(s)
The effects of intensity and volume of physical activity on cerebrovascular health in women across the menopausal transition
Aperçu du projet
Our research project will investigate the relationship between physical activity and brain vascular health in women. The term vascular brain health refers to the health of blood vessels within the brain. To measure brain vascular health, we use cerebrovascular reactivity (CVR) which quantifies the abilities of blood vessels to expand…
Projet en cours
Voir le projet et les chercheursMolecular processes underlying neuromuscular junction denervation in humans with ALS
Aperçu du projet
Amyotrophic lateral sclerosis (ALS) is marked by dysfunction and degeneration of neuromuscular junctions (NMJ). This can be one of the earliest pathological processes observed in ALS. Past investigations demonstrated NMJ dysfunction and a period of denervation-reinnervation cycling occurs before motor neuron loss. Additionally, some evidence suggests the rescue of motor…
Projet en cours
Voir le projet et les chercheursRoutine enfant TDAH Phase 2
Aperçu du projet
“La bonne intervention, au bon moment, pour le bon enfant”. Le bien-être et l’amélioration des capacités adaptatives des enfants ayant des troubles du neurodéveloppement nécessitent des interventions personnalisées dans le temps, l’intensité, les modalités, Malheureusement, bien que ce principe soit très largement reconnu, la réalité des enfants et de leur…
Projet en cours
Voir le projet et les chercheursFunctional connectivity-guided rTMS for personalized treatment of apathy
Aperçu du projet
Nearly half the people affected with Alzheimer’s disease will at some point show reduced motivation to perform their daily activities or participate in activities they previously enjoyed. They may also show fewer emotions or self-initiative in their daily lives. Such a reduction in behavior is termed as apathy and affects…
Projet en cours
Voir le projet et les chercheursDynamic interplay of vascular injury and inflammation on AD progression
Aperçu du projet
Background: As we age, our blood vessels (“vasculature”) can become damaged, leading to a lack of oxygen and nutrients being supplied to the brain. Such vascular damage can increase the risk of Alzheimer's disease (AD) by up to three times. The brain has specialized immune cells, called astrocytes and microglia,…