Répertoire des subventions financées

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558 ésultat(s) trouvé(s)

Detection and prevention of pypermutant glioma in children and young adults

  • Type de programme

    Team grants

  • Domaine de recherche

    Cancer

  • Disease Area

    Brain Cancer

  • Compétition

    CCS/CIHR/BC Spark Grant: Novel Technology Applications in Cancer Prevention and Early Detection

  • Province

    Ontario

  • Date de Début

    2021

  • Montant total du financement

    $149,878

  • Contribution Santé Canada

    $74,939

Aperçu du projet

Need for project: Replication repair deficiency (RRD) is a genetic condition that significantly increases the risk of developing cancer, particularly early in life. Gliomas are the most common brain tumour seen in children and young adults (CAYA), and occur frequently in RRD. Currently, the prevalence of RRD has not been…

Advanced multi-functional in vivo retinal imaging for ocular oncology

  • Type de programme

    Team grants

  • Domaine de recherche

    Cancer

  • Disease Area

    Brain Cancer

  • Compétition

    CCS/CIHR/BC Spark Grant: Novel Technology Applications in Cancer Prevention and Early Detection

  • Province

    British Columbia

  • Date de Début

    2021

  • Montant total du financement

    $146,900

  • Contribution Santé Canada

    $73,450

Aperçu du projet

Need for project: Choroidal tumors present clinicians with many challenges. The overlap between clinical and imaging findings combined with the difficulty of performing choroidal biopsies can create diagnostic dilemmas. Obtaining a diagnosis is paramount in optimizing patient outcomes, minimizing systemic complications and reducing inadvertent treatment of benign lesions. There continues…

Physical fingerprints of single extracellular vesicles for liquid biopsy in brain cancer

  • Type de programme

    Team grants

  • Domaine de recherche

    Cancer

  • Disease Area

    Brain Cancer

  • Compétition

    CCS/CIHR/BC Spark Grant: Novel Technology Applications in Cancer Prevention and Early Detection

  • Province

    Québec

  • Date de Début

    2021

  • Montant total du financement

    $150,000

  • Contribution Santé Canada

    $75,000

Aperçu du projet

Need for project: Glioblastoma (GBM) is an incurable brain cancer that changes rapidly confounding standard diagnostic and therapeutic methods. These changes in molecular composition can be captured by bits of cancer cells known as extracellular vesicles (EVs) found in blood of patients (liquid biopsy), but it is very difficult to…

Radiomics and machine learning based non-invasive biomarkers for prediction of peritumoral invasion in brain metastases

  • Type de programme

    Team grants

  • Domaine de recherche

    Cancer

  • Disease Area

    Brain Cancer

  • Compétition

    CCS/CIHR/BC Spark Grant: Novel Technology Applications in Cancer Prevention and Early Detection

  • Province

    Québec

  • Date de Début

    2021

  • Montant total du financement

    $150,000

  • Contribution Santé Canada

    $75,000

Aperçu du projet

Need for project: Treatment of brain metastases (BrM) includes a combination of surgery and radiation therapy (RT). Recurrence after treatment is a problem that limits survival and quality of life. Our team has discovered that highly invasive growth of BrM is associated with recurrence and sensitivity to particular systemic treatments.…

Precision diagnosis and prognosis of primary and metastatic brain tumours using DNA methylation profiling in liquid biopsy

  • Type de programme

    Team grants

  • Domaine de recherche

    Cancer

  • Disease Area

    Brain Cancer

  • Compétition

    CCS/CIHR/BC Spark Grant: Novel Technology Applications in Cancer Prevention and Early Detection

  • Province

    Ontario

  • Date de Début

    2021

  • Montant total du financement

    $149,760

  • Contribution Santé Canada

    $74,880

Aperçu du projet

Need for project: More sensitive molecular tools are needed in the field of neuro-oncology to enable early detection, more accurate diagnosis, and prediction of outcome for brain tumors. We have early experience in establishing that DNA methylome signatures in liquid biopsy can be used as a highly sensitive approach for…