Répertoire des subventions financées

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Reversing Cardiac Chaos: Cardiac Benefits of Epidural Electrical Stimulation (EES) in Acute Spinal Cord Injury Mice

  • Type de subvention

    Capacity building grants

  • Compétition

    Rising Stars Trainee Awards

  • Province

    Alberta

  • Date de Début

    2024

  • Montant total du financement

    $5,000

Aperçu du projet

Background: A spinal cord injury (SCI) disrupts communication between supraspinal cardiovascular control centers and the regions of the spinal cord that regulate cardiac function. The consequence is a dysregulation of the cardiovascular system and a three-fold increased risk of heart disease. We recently demonstrated that epidural electrical stimulation (EES) targeting…

Investigating the interaction between cell adhesion molecule 2 (CADM2) genetic variation and cannabinoids using behavioural and neurochemical assessments

  • Type de subvention

    Capacity building grants

  • Compétition

    Rising Stars Trainee Awards

  • Province

    Ontario

  • Date de Début

    2024

  • Montant total du financement

    $3,026

Aperçu du projet

CADM2 is a gene located on chromosome 3. This gene is primary expressed in the brain, especially in regions that are known to be involved in substance-use related behaviours, cognition, and impulsivity. Previous research has shown that variations in the CADM2 gene are connected to different attentional and impulsivity traits.…

Ultrasound-assisted modulation of endothelial immunobiology in the context of CARNK-92 cell chemotaxis for cellular immunotherapy

  • Type de subvention

    Capacity building grants

  • Compétition

    Rising Stars Trainee Awards

  • Province

    Québec

  • Date de Début

    2024

  • Montant total du financement

    $5,000

Aperçu du projet

Cellular immunotherapy has met initial exciting success against blood-borne cancers yet remains severely hindered in the context of solid tumors, including glioblastoma. One of the main reasons for this is the immune-suppressive tumor microenvironment, in which key adhesion molecules are downregulated to hinder immune cell trafficking, and the secretion of…

Multimodal precision neuroimaging of the individual human brain at ultra-high field

  • Type de subvention

    Capacity building grants

  • Compétition

    Rising Stars Trainee Awards

  • Province

    Québec

  • Date de Début

    2024

  • Montant total du financement

    $4,975

Aperçu du projet

Multimodal neuroimaging allows for a non-invasive examination of the structure and function of the human brain. The traditional way of analyzing data has for a long time been to acquire short, standard sessions and to average data across individuals, which limits the specificity of findings and may in some cases…

The impact of TREM2 polymorphism on microglial function in Alzheimer’s Disease pathogenesis

  • Type de subvention

    Capacity building grants

  • Compétition

    Rising Stars Trainee Awards

  • Province

    Ontario

  • Date de Début

    2024

  • Montant total du financement

    $3,500

Aperçu du projet

Genetic variation in the TREM2 protein is associated with an increased risk of developing Alzheimer’s disease. TREM2, expressed on the surface of brain immune cells (microglia), helps microglia activate, clear harmful proteins like amyloid beta (Aβ), and prevent their buildup—key processes in protecting against AD. However, a variant near the…