Répertoire des subventions financées

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Targeting a keystone bacterial periodontal pathogen to mitigate neurodegenerative changes in Alzheimer’s disease

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Compétition

    Alzheimer Society Research Program (ASRP)

  • Province

    Québec

  • Date de Début

    2025

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

Periodontal disease (PdD) has links and associations to Alzheimer’s diseases (AD). There is still no imminent cure for PdD, and treatment requires ongoing dental care. The bacterium Porphyromonas gingivalis (PG) plays a major role in gum disease and is also associated with AD. We have identified a small protein, naturally…

PET imaging of Alzheimer’s-induced inflammation to monitor progression and therapy response using a novel fructose-based radiotracer

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Compétition

    Alzheimer Society Research Program (ASRP)

  • Province

    Ontario

  • Date de Début

    2025

  • Montant total du financement

    $99,986

  • Contribution Santé Canada

    $49,993

Aperçu du projet

Alzheimer's Disease (AD) is tough to diagnose as it requires understanding patient history, symptoms, blood tests,and brain scans. Current brain scans mainly look at how glucose and amyloid (a protein) behave, but these tests aren't very reliable. Researchers aim to create a new brain scan that can better identify AD…

Deep histological and pathological phenotyping of sporadic dementia

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Compétition

    Alzheimer Society Research Program (ASRP)

  • Province

    British Columbia

  • Date de Début

    2025

  • Montant total du financement

    $200,000

  • Contribution Santé Canada

    $100,000

Aperçu du projet

Patients with dementia may have pure Alzheimer Disease (AD) pathology or a combination of pathologies called mixed dementia. In general, patients with younger age of onset (less than 65 years) tend to exhibit pure AD pathology, whereas older individuals are more likely to develop mixed dementia. Among the most common…

Signatures of early life stress as a risk factor for Alzheimer’s disease

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Compétition

    Alzheimer Society Research Program (ASRP)

  • Province

    Alberta

  • Date de Début

    2025

  • Montant total du financement

    $200,000

  • Contribution Santé Canada

    $100,000

Aperçu du projet

Childhood stress increases the risk of Alzheimer’s Disease (AD). Early signs of AD appear in a part of the brain that produces serotonin, a chemical important for mood and memory-both of which are affected in AD. Serotonin is also sensitive to childhood trauma. Although there is a connection between early…

Ensuring equitable access to inpatient rehabilitation for people living with dementia: An effectiveness-implementation randomized trial

  • Type de subvention

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Compétition

    Alzheimer Society Research Program (ASRP)

  • Province

    Ontario

  • Date de Début

    2025

  • Montant total du financement

    $200,000

  • Contribution Santé Canada

    $100,000

Aperçu du projet

One in five older adults with dementia is hospitalized each year. One in three hospitalized older adults will lose independence in transferring, eating, ambulating, dressing, or bathing, which increases nursing home admission risk; this risk is 36% greater in people living with dementia (PLWD). Rehabilitation could decrease this risk, but…