Répertoire des subventions financées

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The development of an online peer navigation intervention for youth with neurodevelopmental disabilities

  • Type de programme

    Capacity building grants

  • Domaine de recherche

    Neurodevelopment

  • Compétition

    KBHN Early Career Investigator & Mentorship Awards

  • Province

    Ontario

  • Date de Début

    2022

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

Background: Transition from the pediatric to adult health care system is a multi-faceted process that should include medical and psychosocial considerations. Despite the importance of ensuring successful transition and independence in the community, and the significant detrimental health outcomes related to poor transition, there has been limited implementation of effective…

Enhancing Supports for Autistic Post-Secondary Students at the University of Calgary

  • Type de programme

    Capacity building grants

  • Domaine de recherche

    Neurodevelopment

  • Compétition

    KBHN Early Career Investigator & Mentorship Awards

  • Province

    Alberta

  • Date de Début

    2022

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

Autistic individuals are disproportionately under-represented in post-secondary institutions, with only 35% of students with autism pursuing post-secondary education. Of those individuals with autism who do enter post-secondary environments, only 39% are likely to graduate. A lack of available autism specific supports has been suggested to interfere with successful post-secondary education.…

Neuronal reprogramming as a novel therapeutic strategy to treat Amyotrophic lateral sclerosis

  • Type de programme

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Compétition

    ALS Canada-Brain Canada Trainee Program 2022

  • Province

    Ontario

  • Date de Début

    2022

  • Montant total du financement

    $165,000

  • Contribution Santé Canada

    $82,500

Aperçu du projet

The demonstration that mature somatic cells can be converted to new, heterologous cell types, now termed “cellular reprogramming”, led to the 2012 Nobel Prize in Physiology or Medicine, and sparked an explosion of studies investigating the therapeutic potential of such an approach. Direct neuronal reprogramming refers to the conversion of…

Aberrant tRNA function exacerbates TDP-43 misfolding and toxicity in cellular models of ALS

  • Type de programme

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    ALS FR

  • Compétition

    ALS Canada-Brain Canada Trainee Program 2022

  • Province

    Ontario

  • Date de Début

    2022

  • Montant total du financement

    $75,000

  • Contribution Santé Canada

    $37,500

Aperçu du projet

Aberrant tRNA processing and function has the capacity to exacerbate misfolding of ALS-associated proteins and the ensuing toxicity. tRNAs mainly function to recruit amino acids to ribosomes, allowing faithful translation of mRNA molecules. Metabolites of processed tRNAs also function in cellular stress responses, such as inducing stress granule formation. The…

Elucidating the role of stress granules dynamics in the pathogenesis of ALS

  • Type de programme

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    ALS FR

  • Compétition

    ALS Canada-Brain Canada Trainee Program 2022

  • Province

    Ontario

  • Date de Début

    2022

  • Montant total du financement

    $75,000

  • Contribution Santé Canada

    $37,500

Aperçu du projet

The lifetime risk of developing amyotrophic lateral sclerosis (ALS) is approximately 1 in 350 for men and 1 in 440 for women, making it the most common adult-onset motor neuron disease. There is no cure and poor prognosis for this devastating neurodegenerative disease, resulting in increased mortality and morbidity. With…